BACKGROUND: The aim of this study was to compare the efficacy, safety, antiplaque and antigingivitis properties of a herbal mouthwash with chlorhexidine mouthwash. METHODS: A double-blinded randomized clinical trial was conducted among 72 undergraduate students with age group 18-24 years. They were randomly divided into three mouthwash group with 24 participants in each group. Group A (herbal), Group B (chlorhexidine) and Group C (normal saline).The Turesky et al. 1970 plaque index and Loe and Silness 1963 gingival index was recorded. Student's t-test and one-way ANOVA were used to test the significance. RESULTS: A statistically highly significant difference was obtained between mouthwash B and C (p=0.00) and a significant difference between mouthwash A and C (p=0.004), showing that chlorhexidine was superior to herbal mouthwash and saline. However, there was a nonsignificant difference between mouthwash A and B (p=0.435) showing that herbal and chlorhexidine mouthwash was equally effective in reducing plaque and gingivitis. CONCLUSIONS: The efficacy of herbal mouthwash was equally effective in reducing plaque and gingivitis as compared to chlorhexidine mouthwash and may be considered as a good alternative. The chlorhexidine mouthwash was reported with many side effects which limits its acceptability and long-term use, whereas the presently tested herbal mouthwash had no side effects apart from mild burning sensation.
RCT Entities:
BACKGROUND: The aim of this study was to compare the efficacy, safety, antiplaque and antigingivitis properties of a herbal mouthwash with chlorhexidine mouthwash. METHODS: A double-blinded randomized clinical trial was conducted among 72 undergraduate students with age group 18-24 years. They were randomly divided into three mouthwash group with 24 participants in each group. Group A (herbal), Group B (chlorhexidine) and Group C (normal saline).The Turesky et al. 1970 plaque index and Loe and Silness 1963 gingival index was recorded. Student's t-test and one-way ANOVA were used to test the significance. RESULTS: A statistically highly significant difference was obtained between mouthwash B and C (p=0.00) and a significant difference between mouthwash A and C (p=0.004), showing that chlorhexidine was superior to herbal mouthwash and saline. However, there was a nonsignificant difference between mouthwash A and B (p=0.435) showing that herbal and chlorhexidine mouthwash was equally effective in reducing plaque and gingivitis. CONCLUSIONS: The efficacy of herbal mouthwash was equally effective in reducing plaque and gingivitis as compared to chlorhexidine mouthwash and may be considered as a good alternative. The chlorhexidine mouthwash was reported with many side effects which limits its acceptability and long-term use, whereas the presently tested herbal mouthwash had no side effects apart from mild burning sensation.
Authors: Sunitha Janardhanan; Jaideep Mahendra; A S Smiline Girija; Little Mahendra; Vijayashree Priyadharsini Journal: J Clin Diagn Res Date: 2017-01-01
Authors: Patrice James; Helen V Worthington; Carmel Parnell; Mairead Harding; Thomas Lamont; Andrea Cheung; Helen Whelton; Philip Riley Journal: Cochrane Database Syst Rev Date: 2017-03-31
Authors: Briana Joy Travis; James Elste; Feng Gao; Bo Young Joo; Maria Cuevas-Nunez; Ellen Kohlmeir; Vaibhav Tiwari; John C Mitchell Journal: Oral Dis Date: 2022-07-16 Impact factor: 4.068