Literature DB >> 24698405

Higher body mass index in adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus is associated with lower risk HLA genes.

S Fourlanos1, S Elkassaby1, M D Varney2, P G Colman3, L C Harrison4.   

Abstract

We hypothesised that higher body weight, a proposed risk factor for type 1 diabetes mellitus, would be associated with increased penetrance of lower risk genes. In adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus we found that higher body mass index was associated with the absence of the highest risk HLA genes.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Body weight; Gene penetrance; HLA; LADA; Type 1 diabetes mellitus

Mesh：

Substances：

Year:  2014        PMID： 24698405     DOI： 10.1016/j.diabres.2014.03.009

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  6 in total

Review 1.  Macrovascular disease and risk factors in youth with type 1 diabetes: time to be more attentive to treatment?

Authors:  Petter Bjornstad; Kim C Donaghue; David M Maahs
Journal:  Lancet Diabetes Endocrinol       Date:  2018-02-20       Impact factor: 32.069

2.  Adiposity Impacts Intrarenal Hemodynamic Function in Adults With Long-standing Type 1 Diabetes With and Without Diabetic Nephropathy: Results From the Canadian Study of Longevity in Type 1 Diabetes.

Authors:  Petter Bjornstad; Julie A Lovshin; Yuliya Lytvyn; Genevieve Boulet; Leif E Lovblom; Omar N Alhuzaim; Mohammed A Farooqi; Vesta Lai; Josephine Tse; Leslie Cham; Andrej Orszag; Daniel Scarr; Alanna Weisman; Hillary A Keenan; Michael H Brent; Narinder Paul; Vera Bril; Bruce A Perkins; David Z I Cherney
Journal:  Diabetes Care       Date:  2018-02-02       Impact factor: 19.112

3.  Genetics: Is LADA just late onset type 1 diabetes?

Authors:  M Hernández; Y Nóvoa-Medina; R Faner; E Palou; A Esquerda; E Castelblanco; A M Wägner; D Mauricio
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-10       Impact factor: 6.055

4.  Adult-onset autoimmune diabetes identified by glutamic acid decarboxylase autoantibodies: a retrospective cohort study.

Authors:  Eri Wada; Takeshi Onoue; Tamaki Kinoshita; Ayaka Hayase; Tomoko Handa; Masaaki Ito; Mariko Furukawa; Takayuki Okuji; Tomoko Kobayashi; Shintaro Iwama; Mariko Sugiyama; Hiroshi Takagi; Daisuke Hagiwara; Hidetaka Suga; Ryoichi Banno; Motomitsu Goto; Hiroshi Arima
Journal:  Diabetologia       Date:  2021-07-15       Impact factor: 10.122

Review 5.  Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges.

Authors:  Nuria Vilarrasa; Patricia San Jose; Miguel Ángel Rubio; Albert Lecube
Journal:  Diabetes Metab Syndr Obes       Date:  2021-06-21       Impact factor: 3.168

6.  Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes.

Authors:  Maria C Magnus; Sjurdur F Olsen; Charlotta Granstrom; Nicolai A Lund-Blix; Jannet Svensson; Jesper Johannesen; Abigail Fraser; Torild Skrivarhaug; Geir Joner; Pål R Njølstad; Ketil Størdal; Lars C Stene
Journal:  Int J Epidemiol       Date:  2018-04-01       Impact factor: 7.196
  6 in total

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