Literature DB >> 24697971

The role of serum albumin in the prediction of malnutrition in patients at least five yr after heart transplantation.

Günther Prenner1, Andrä Wasler, Astrid Fahrleinter-Pammer, Georg Werkgartner, Hans Jörg Mischinger, Stephan Koter, Regina Roller, Doris Wagner.   

Abstract

OBJECTIVES: Malnutrition after heart transplantation (HTX) is related to graft sclerosis. The risk for malnutrition is often underestimated by conventional measurements. We aimed to compare these with objective assessors for malnutrition.
METHODS: Recipients at least five yr after HTX were included. Body mass index (BMI), bioimpedance analysis (BIA), serum albumin (SA) and subjective global assessment (SGA) malnutrition, and concomitant diseases were assessed. The BIA was used as gold standard, and a phase difference (PD) <4 was defined as cutoff.
RESULTS: Sixty recipients (47 male, 13 female) were analyzed. The prevalence of malnutrition was according to SGA 6.6% (4/60), BMI 8.3% (5/60), SA 31.6% (19/60), and BIA 48.3% (19/60). PD values did not correlate with BMI (r = 0.118; p = 0.079) or SGA (r = 0.289; p = 0.65), but with SA (r = 0.458; p = 0.001). Multivariate analysis yield SA and sCr as independent predictors for an existing malnutrition. ROC analysis showed an area under the receiver operating characteristic curve of 0.606 for SA as compared to 0.515 for the BMI and 0.698 for sCr in the prediction of existing malnutrition as defined by the PD.
CONCLUSION: The BMI or the SGA did not show as much power in predicting an existing alimentary deficiency for heart recipients as did SA.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  body mass index; heart transplantation; malnutrition; serum albumin

Mesh:

Substances:

Year:  2014        PMID: 24697971     DOI: 10.1111/ctr.12370

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


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