Zeming Liu1, Longqiang Wang1, Pengfei Yi1, Cong-Yi Wang2, Tao Huang1. 1. Department of General Surgery, Affiliated Union Hospital, Tongji Medical College Wuhan, China. 2. The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, Hubei Province, China.
Abstract
OBJECTIVE: To evaluate the risk factors of central lymph node metastasis of papillary thyroid microcarcinoma. METHOD: Published articles about papillary thyroid microcarcinoma were searched in PubMed, MEDLINE and EMBASE until October 2013 to examine the risky factors of central lymph node metastasis. Software RevMan 5.0 was used for meta-analysis. RESULTS: Within the patients suffering papillary thyroid microcarcinoma underwent thyroidectomy plus prophylactic central lymph node dissection, tumor size, multifocality and capsular invasion have statistically relevant association with central lymph node metastasis, but no relation was observed associated with sex and age. CONCLUSION: The papillary thyroid microcarcinoma should be considered central lymph node metastasis when tumor size ≥0.5 cm, multifocality and have capsular invasion.
OBJECTIVE: To evaluate the risk factors of central lymph node metastasis of papillary thyroid microcarcinoma. METHOD: Published articles about papillary thyroid microcarcinoma were searched in PubMed, MEDLINE and EMBASE until October 2013 to examine the risky factors of central lymph node metastasis. Software RevMan 5.0 was used for meta-analysis. RESULTS: Within the patients suffering papillary thyroid microcarcinoma underwent thyroidectomy plus prophylactic central lymph node dissection, tumor size, multifocality and capsular invasion have statistically relevant association with central lymph node metastasis, but no relation was observed associated with sex and age. CONCLUSION: The papillary thyroid microcarcinoma should be considered central lymph node metastasis when tumor size ≥0.5 cm, multifocality and have capsular invasion.
Entities:
Keywords:
Risk factors; central lymph node metastasis; papillary thyroid carcinoma
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