Gerardo Gómez-Moreno1, Antonio Aguilar-Salvatierra2, Jerónimo Rubio Roldán3, Javier Guardia2, Jordi Gargallo4, José Luis Calvo-Guirado5. 1. Department of Special Care in Dentistry, Pharmacological Research in Dentistry, Periodontology and Implant Dentistry, Faculty of Dentistry, University of Granada, Granada, Spain. 2. Department of Pharmacological Research in Dentistry, Faculty of Dentistry, University of Granada, Granada, Spain. 3. Periodontology and Implant Dentistry, Faculty of Dentistry, Universidad de Granada, Granada, Spain. 4. Department of Dentistry, Faculty of Dentistry, Universitat Internacional de Catalunya, Barcelona, Spain. 5. Department of Implant Dentistry, Implant Dentistry and Biomaterials, School of Medicine and Dentistry, University of Murcia, Murcia, Spain.
Abstract
OBJECTIVE: The aim of this study was to analyze the changes produced in peri-implant tissues in type 2 diabetes mellitus patients with different glycemia levels, measured by monitoring glycated hemoglobin A1c (HbA1c), over a period of 3 years following dental implant placement. MATERIALS AND METHODS: Sixty-seven patients were divided into four groups according to their HbA1c levels: 21 patients in Group 1 (<6); 24 patients in Group 2 (6.1-8); and 11 patients in Group 3 (8.1-10) and Group 4 (>10.1). Each patient received one implant. All implants were placed in the anterior zone of the maxilla. The variables selected to assess the general state of patients' peri-implant health were as follows: probing depth, bleeding on probing, and marginal bone loss. RESULTS: Marginal bone loss was found to increase in relation to increases in HbA1c levels. Bleeding on probing showed statistically significant differences between groups. When the peri-implant area was probed, mean levels of bleeding varied from 0.43 in Group 1 at 1 year after implant surgery to 0.62 in Group 4 (P = 0.042 between the four study groups). After the second year, greater bleeding on probing was observed in Group 4 (0.63) in comparison with groups with lower HbA1c levels. Peri-implant pocket depths presented values that were too low to be considered pathological and without statistically significant differences between the study groups. CONCLUSION: Implant therapies for diabetic patients can be predictable, providing these patients fall within controlled ranges of glycemia over time, assessed by monitoring HbA1c levels.
OBJECTIVE: The aim of this study was to analyze the changes produced in peri-implant tissues in type 2 diabetes mellituspatients with different glycemia levels, measured by monitoring glycated hemoglobin A1c (HbA1c), over a period of 3 years following dental implant placement. MATERIALS AND METHODS: Sixty-seven patients were divided into four groups according to their HbA1c levels: 21 patients in Group 1 (<6); 24 patients in Group 2 (6.1-8); and 11 patients in Group 3 (8.1-10) and Group 4 (>10.1). Each patient received one implant. All implants were placed in the anterior zone of the maxilla. The variables selected to assess the general state of patients' peri-implant health were as follows: probing depth, bleeding on probing, and marginal bone loss. RESULTS:Marginal bone loss was found to increase in relation to increases in HbA1c levels. Bleeding on probing showed statistically significant differences between groups. When the peri-implant area was probed, mean levels of bleeding varied from 0.43 in Group 1 at 1 year after implant surgery to 0.62 in Group 4 (P = 0.042 between the four study groups). After the second year, greater bleeding on probing was observed in Group 4 (0.63) in comparison with groups with lower HbA1c levels. Peri-implant pocket depths presented values that were too low to be considered pathological and without statistically significant differences between the study groups. CONCLUSION: Implant therapies for diabeticpatients can be predictable, providing these patients fall within controlled ranges of glycemia over time, assessed by monitoring HbA1c levels.
Authors: Mario Dioguardi; Stefania Cantore; Salvatore Scacco; Cristian Quarta; Diego Sovereto; Francesca Spirito; Mario Alovisi; Giuseppe Troiano; Riccardo Aiuto; Daniele Garcovich; Vito Crincoli; Luigi Laino; Michele Covelli; Annarita Malcangi; Lorenzo Lo Muzio; Andrea Ballini; Michele Di Cosola Journal: J Pers Med Date: 2022-02-08
Authors: Carlos Alexandre Soares Andrade; João Lucas Carvalho Paz; Gabriel Simino de Melo; Nour Mahrouseh; Alessandro Lourenço Januário; Lucas Raineri Capeletti Journal: Clin Oral Investig Date: 2021-09-29 Impact factor: 3.573