Literature DB >> 24682511

Frequent occurrence of non-malignant genetic alterations in clinical grade mesenchymal stromal cells expanded for cell therapy protocols.

Chiara Capelli1, Olga Pedrini1, Gisella Cassina2, Orietta Spinelli3, Silvia Salmoiraghi3, Josée Golay1, Alessandro Rambaldi3, Ursula Giussani2, Martino Introna4.   

Abstract

Keywords:  cell therapy protocols; mesenchymal stromal cells; non malignant genetic alterations

Mesh：

Year:  2014        PMID： 24682511      PMCID： PMC4040903          DOI： 10.3324/haematol.2014.104711

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  Retraction: Spontaneous human adult stem cell transformation.

Authors:  Ricardo de la Fuente; Antonio Bernad; Javier Garcia-Castro; Maria C Martin; Juan C Cigudosa
Journal:  Cancer Res       Date:  2010-08-15       Impact factor: 12.701

2.  Cytogenetic analysis of human bone marrow-derived mesenchymal stem cells passaged in vitro.

Authors:  Zhen-Xing Zhang; Li-Xue Guan; Kun Zhang; Shouxian Wang; Pei-Cheng Cao; Yong-He Wang; Zhe Wang; Long-Jun Dai
Journal:  Cell Biol Int       Date:  2006-11-29       Impact factor: 3.612

3.  Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells.

Authors:  Uri Ben-David; Yoav Mayshar; Nissim Benvenisty
Journal:  Cell Stem Cell       Date:  2011-08-05       Impact factor: 24.633

Review 4.  Risk of tumorigenicity in mesenchymal stromal cell-based therapies--bridging scientific observations and regulatory viewpoints.

Authors:  Lisbeth Barkholt; Egbert Flory; Veronika Jekerle; Sophie Lucas-Samuel; Peter Ahnert; Louise Bisset; Dirk Büscher; Willem Fibbe; Arnaud Foussat; Marcel Kwa; Olivier Lantz; Romaldas Mačiulaitis; Tiina Palomäki; Christian K Schneider; Luc Sensebé; Gérard Tachdjian; Karin Tarte; Lucie Tosca; Paula Salmikangas
Journal:  Cytotherapy       Date:  2013-04-18       Impact factor: 5.414

5.  Spontaneous human adult stem cell transformation.

Authors:  Daniel Rubio; Javier Garcia-Castro; María C Martín; Ricardo de la Fuente; Juan C Cigudosa; Alison C Lloyd; Antonio Bernad
Journal:  Cancer Res       Date:  2005-04-15       Impact factor: 12.701

6.  Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

Authors:  S I Shin; V H Freedman; R Risser; R Pollack
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205

7.  Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients.

Authors:  Martino Introna; Giovanna Lucchini; Erica Dander; Stefania Galimberti; Attilio Rovelli; Adriana Balduzzi; Daniela Longoni; Fabio Pavan; Francesca Masciocchi; Alessandra Algarotti; Caterina Micò; Anna Grassi; Sara Deola; Irene Cavattoni; Giuseppe Gaipa; Daniela Belotti; Paolo Perseghin; Matteo Parma; Enrico Pogliani; Josee Golay; Olga Pedrini; Chiara Capelli; Sergio Cortelazzo; Giovanna D'Amico; Andrea Biondi; Alessandro Rambaldi; Ettore Biagi
Journal:  Biol Blood Marrow Transplant       Date:  2013-12-07       Impact factor: 5.742

8.  Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.

Authors:  Maria Ester Bernardo; Nadia Zaffaroni; Francesca Novara; Angela Maria Cometa; Maria Antonietta Avanzini; Antonia Moretta; Daniela Montagna; Rita Maccario; Raffaella Villa; Maria Grazia Daidone; Orsetta Zuffardi; Franco Locatelli
Journal:  Cancer Res       Date:  2007-10-01       Impact factor: 12.701

9.  Chromosomal aberrations and deoxyribonucleic acid single-strand breaks in adipose-derived stem cells during long-term expansion in vitro.

Authors:  Katrin Froelich; Johannes Mickler; Gudrun Steusloff; Antje Technau; Mario Ramos Tirado; Agmal Scherzed; Stephan Hackenberg; Andreas Radeloff; Rudolf Hagen; Norbert Kleinsasser
Journal:  Cytotherapy       Date:  2013-05-01       Impact factor: 5.414

10.  The washouts of discarded bone marrow collection bags and filters are a very abundant source of hMSCs.

Authors:  Chiara Capelli; Agnese Salvade; Olga Pedrini; Valentina Barbui; Elisa Gotti; Gianmaria Borleri; Benedetta Cabiati; Daniela Belotti; Paolo Perseghin; Piero Bellavita; Andrea Biondi; Ettore Biagi; Alessandro Rambaldi; Josee Golay; Martino Introna
Journal:  Cytotherapy       Date:  2009       Impact factor: 5.414
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  15 in total

1.  Microscale Biomaterials with Bioinspired Complexity of Early Embryo Development and in the Ovary for Tissue Engineering and Regenerative Medicine.

Authors:  Xiaoming He
Journal:  ACS Biomater Sci Eng       Date:  2016-12-01

2.  Hydrogel Encapsulation Facilitates Rapid-Cooling Cryopreservation of Stem Cell-Laden Core-Shell Microcapsules as Cell-Biomaterial Constructs.

Authors:  Gang Zhao; Xiaoli Liu; Kaixuan Zhu; Xiaoming He
Journal:  Adv Healthc Mater       Date:  2017-11-27       Impact factor: 9.933

3.  Chromosomal stability of mesenchymal stromal cells during in vitro culture.

Authors:  Brian G Stultz; Kathleen McGinnis; Elaine E Thompson; Jessica L Lo Surdo; Steven R Bauer; Deborah A Hursh
Journal:  Cytotherapy       Date:  2016-01-15       Impact factor: 5.414

4.  Nanoparticle-mediated intracellular delivery enables cryopreservation of human adipose-derived stem cells using trehalose as the sole cryoprotectant.

Authors:  Wei Rao; Haishui Huang; Hai Wang; Shuting Zhao; Jenna Dumbleton; Gang Zhao; Xiaoming He
Journal:  ACS Appl Mater Interfaces       Date:  2015-02-24       Impact factor: 9.229

5.  Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton's jelly and bone marrow-derived mesenchymal stem cells.

Authors:  Aristea K Batsali; Charalampos Pontikoglou; Dimitrios Koutroulakis; Konstantia I Pavlaki; Athina Damianaki; Irene Mavroudi; Kalliopi Alpantaki; Elisavet Kouvidi; George Kontakis; Helen A Papadaki
Journal:  Stem Cell Res Ther       Date:  2017-04-26       Impact factor: 6.832

Review 6.  Cross-Talk Between Mesenchymal Stromal Cells (MSCs) and Endothelial Progenitor Cells (EPCs) in Bone Regeneration.

Authors:  Cyril Bouland; Pierre Philippart; Didier Dequanter; Florent Corrillon; Isabelle Loeb; Dominique Bron; Laurence Lagneaux; Nathalie Meuleman
Journal:  Front Cell Dev Biol       Date:  2021-05-13

7.  Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells.

Authors:  Margarita Pustovalova; Anna Grekhova; Тatiana Astrelina; Viktoria Nikitina; Ekaterina Dobrovolskaya; Yulia Suchkova; Irina Kobzeva; Darya Usupzhanova; Natalia Vorobyeva; Aleksandr Samoylov; Andrey Bushmanov; Ivan V Ozerov; Alex Zhavoronkov; Sergey Leonov; Dmitry Klokov; Andreyan N Osipov
Journal:  Aging (Albany NY)       Date:  2016-12-11       Impact factor: 5.682

8.  Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells.

Authors:  Jiyeon Kim; Yonggoo Kim; Hayoung Choi; Ahlm Kwon; Dong Wook Jekarl; Seungok Lee; Woori Jang; Hyojin Chae; Jung Rok Kim; Jung Min Kim; Myungshin Kim
Journal:  Cell Death Dis       Date:  2018-01-30       Impact factor: 8.469

Review 9.  Advance in Targeted Immunotherapy for Graft-Versus-Host Disease.

Authors:  Lingling Zhang; Jianhua Yu; Wei Wei
Journal:  Front Immunol       Date:  2018-05-16       Impact factor: 7.561

10.  Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition.

Authors:  Xuanwen Bao; Jing Wang; Guangming Zhou; Attila Aszodi; Veronika Schönitzer; Harry Scherthan; Michael J Atkinson; Michael Rosemann
Journal:  FEBS Open Bio       Date:  2020-06-09       Impact factor: 2.693
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