Natal Santos da Silva1, Vitor Dantas Muniz2, Cássia Fernanda Estofolete3, Guilherme Henrique Campos Furtado4, Fernando Gongora Rubio2. 1. Postgraduate Department, Medical College of São José do Rio Preto, São Paulo, Brazil; Medical Sciences Department, Medical College, Union of Colleges of the Great Lakes, São José do Rio Preto, São Paulo, Brazil. Electronic address: natalss@gmail.com. 2. Department of Infectious and Parasitic Diseases, Hospital de Base, São José do Rio Preto, São Paulo, Brazil. 3. Department of Infectious and Parasitic Diseases, Hospital de Base, São José do Rio Preto, São Paulo, Brazil; Virology Laboratory, Medical College of São José do Rio Preto, São Paulo, Brazil. 4. Hospital Epidemiology Committee, Department of Infectious Diseases, Federal University of São Paulo, São Paulo, Brazil.
Abstract
BACKGROUND: This study aimed to evaluate a different methodology for addressing the evolution of nosocomial bacteremia by vancomycin-resistant enterococci (VRE) in a hospital setting. METHODS: In this retrospective cohort study, data were collected from the date of first registration up to December 2008 from the electronic medical records of patients with VRE bacteremia in a school hospital. RESULTS: Thirty cases of VRE bacteremia and 274 cases of vancomycin-susceptible enterococci (VSE) bacteremia were identified. The average age of the patients was 56 years. The rates of Enterococcus faecium and Enterococcus faecalis in the hospital's intensive care unit (ICU) and wards showed no statistically significant differences. The risk of acquiring VRE bacteremia was at least 3-fold higher in the ICU than in the wards. The risk of death was 2.73-fold higher in patients with VRE bacteremia compared with those with VSE bacteremia. Only one temporal cluster statistically significant of VRE bacteremia was found in the study period. CONCLUSIONS: The identification of temporal clusters can be an important tool to optimize health actions and thereby reduce the burden of operating costs.
BACKGROUND: This study aimed to evaluate a different methodology for addressing the evolution of nosocomial bacteremia by vancomycin-resistant enterococci (VRE) in a hospital setting. METHODS: In this retrospective cohort study, data were collected from the date of first registration up to December 2008 from the electronic medical records of patients with VRE bacteremia in a school hospital. RESULTS: Thirty cases of VRE bacteremia and 274 cases of vancomycin-susceptible enterococci (VSE) bacteremia were identified. The average age of the patients was 56 years. The rates of Enterococcus faecium and Enterococcus faecalis in the hospital's intensive care unit (ICU) and wards showed no statistically significant differences. The risk of acquiring VRE bacteremia was at least 3-fold higher in the ICU than in the wards. The risk of death was 2.73-fold higher in patients with VRE bacteremia compared with those with VSE bacteremia. Only one temporal cluster statistically significant of VRE bacteremia was found in the study period. CONCLUSIONS: The identification of temporal clusters can be an important tool to optimize health actions and thereby reduce the burden of operating costs.
Authors: Zachary M Burcham; Carl J Schmidt; Jennifer L Pechal; Christopher P Brooks; Jason W Rosch; M Eric Benbow; Heather R Jordan Journal: PLoS One Date: 2019-03-14 Impact factor: 3.240
Authors: S Dubler; M Lenz; S Zimmermann; D C Richter; K H Weiss; A Mehrabi; M Mieth; T Bruckner; M A Weigand; T Brenner; A Heininger Journal: Antimicrob Resist Infect Control Date: 2020-01-31 Impact factor: 4.887