AIM: To compare the development of posterior capsule opacification (PCO) between eyes with and without diabetes mellitus after single-piece hydrophobic acrylic intraocular lens implantation 4 years postoperatively. METHODS: In this prospective, observational case-control study carried out at Iladevi Cataract and IOL Research Centre, Ahmedabad, India, 75 consecutive eyes with diabetes mellitus (cases) were compared with 75 age-matched eyes with age-related cataract (controls). A detailed, preoperative and posterior segment evaluation was carried out in eyes with diabetes mellitus to detect the presence or absence of diabetic retinopathy (DR). The Mann-Whitney U-test was applied to compare the differences in the development of PCO between the two groups. RESULTS: There was no difference in median PCO between cases and controls at 1 month (2.0 vs 1.50, P<0.068), but cases had a higher median PCO at 12 months (2.95 vs 1.30, P<0.001). At 4 years, there was no significant difference in median PCO between cases and controls (3.75 vs 2.25, P=0.273). The duration of diabetes increased the incidence of PCO at 4 years (P=0.02). Severity of DR had no influence on the progress of PCO at 4 years (P=0.69). CONCLUSION: Diabetes mellitus did not increase the incidence of PCO at 4 years. The duration of diabetes increased the risk of PCO. The severity of retinopathy did not influence the development of PCO.
AIM: To compare the development of posterior capsule opacification (PCO) between eyes with and without diabetes mellitus after single-piece hydrophobic acrylic intraocular lens implantation 4 years postoperatively. METHODS: In this prospective, observational case-control study carried out at Iladevi Cataract and IOL Research Centre, Ahmedabad, India, 75 consecutive eyes with diabetes mellitus (cases) were compared with 75 age-matched eyes with age-related cataract (controls). A detailed, preoperative and posterior segment evaluation was carried out in eyes with diabetes mellitus to detect the presence or absence of diabetic retinopathy (DR). The Mann-Whitney U-test was applied to compare the differences in the development of PCO between the two groups. RESULTS: There was no difference in median PCO between cases and controls at 1 month (2.0 vs 1.50, P<0.068), but cases had a higher median PCO at 12 months (2.95 vs 1.30, P<0.001). At 4 years, there was no significant difference in median PCO between cases and controls (3.75 vs 2.25, P=0.273). The duration of diabetes increased the incidence of PCO at 4 years (P=0.02). Severity of DR had no influence on the progress of PCO at 4 years (P=0.69). CONCLUSION:Diabetes mellitus did not increase the incidence of PCO at 4 years. The duration of diabetes increased the risk of PCO. The severity of retinopathy did not influence the development of PCO.
Authors: S A Barman; E J Hollick; J F Boyce; D J Spalton; B Uyyanonvara; G Sanguinetti; W Meacock Journal: Invest Ophthalmol Vis Sci Date: 2000-11 Impact factor: 4.799
Authors: Lloyd E Bender; Christoph Nimsgern; Romina Jose; Hari Jayaram; David J Spalton; Manfred R Tetz; Richard B Packard; William Meacock; James Boyce Journal: J Cataract Refract Surg Date: 2004-04 Impact factor: 3.351
Authors: Abdul Rashid Shaikh; Abdul Haleem Mirani; Muhammad Saleh Memon; Muhammad Faisal Fahim Journal: Pak J Med Sci Date: 2017 May-Jun Impact factor: 1.088
Authors: Johanna Rankenberg; Stefan Rakete; Brandie D Wagner; Jennifer L Patnaik; Christian Henning; Anne Lynch; Marcus A Glomb; Ram H Nagaraj Journal: Exp Eye Res Date: 2021-07-21 Impact factor: 3.770
Authors: Nils Kossack; Christian Schindler; Ines Weinhold; Lennart Hickstein; Moritz Lehne; Jochen Walker; Aljoscha S Neubauer; Dennis Häckl Journal: Z Gesundh Wiss Date: 2017-10-24