Literature DB >> 24674388

An evaluation of multiple phenotypic screening methods for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae.

Elizabeth B Hirsch1, Kai-Tai Chang2, Paola C Zucchi3, Dennis N Francoeur3, Kimberly R Ledesma2, Vincent H Tam4, Todd M Lasco5.   

Abstract

Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae may display MICs to carbapenems within susceptible or intermediate ranges, prompting confirmatory testing. Four phenotypic methods to detect KPC producers were evaluated against a collection of clinical Enterobacteriaceae isolates. Meropenem-phenylboronic acid double disk synergy testing demonstrated the best performance with 100% sensitivity and specificity.
Copyright © 2013 Japanese Society of Chemotherapy and the Japanese Association for Infectious Diseases. All rights reserved.

Entities:  

Keywords:  CRE; Carbapenem; Chromogenic agar; Modified Hodge test; Phenylboronic acid

Mesh：

Substances：

Year:  2013        PMID： 24674388     DOI： 10.1016/j.jiac.2013.10.011

Source DB:  PubMed          Journal:  J Infect Chemother        ISSN： 1341-321X            Impact factor:   2.211


  5 in total

Review 1.  Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.

Authors:  Roberto Viau; Karen M Frank; Michael R Jacobs; Brigid Wilson; Keith Kaye; Curtis J Donskey; Federico Perez; Andrea Endimiani; Robert A Bonomo
Journal:  Clin Microbiol Rev       Date:  2016-01       Impact factor: 26.132

2.  Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics.

Authors:  Elizabeth B Hirsch; Paola C Zucchi; Alice Chen; Brian R Raux; James E Kirby; Christopher McCoy; George M Eliopoulos
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

3.  Performance of modified carbapenem inactivation method and inhibitor-based combined disk test in the detection and distinguishing of carbapenemase producing Enterobacteriaceae.

Authors:  Juan Li; Congrong Li; Xuan Cai; Jinling Shi; Lina Feng; Kewen Tang; Yongqing Tong; Yan Li
Journal:  Ann Transl Med       Date:  2019-10

4.  Volatile metabolic diversity of Klebsiella pneumoniae in nutrient-replete conditions.

Authors:  Christiaan A Rees; Katherine V Nordick; Flavio A Franchina; Alexa E Lewis; Elizabeth B Hirsch; Jane E Hill
Journal:  Metabolomics       Date:  2017-01-12       Impact factor: 4.290

5.  Detection of high-risk carbapenem-resistant Klebsiella pneumoniae and Enterobacter cloacae isolates using volatile molecular profiles.

Authors:  Christiaan A Rees; Mavra Nasir; Agnieszka Smolinska; Alexa E Lewis; Katherine R Kane; Shannon E Kossmann; Orkan Sezer; Paola C Zucchi; Yohei Doi; Elizabeth B Hirsch; Jane E Hill
Journal:  Sci Rep       Date:  2018-09-05       Impact factor: 4.379
  5 in total

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