Literature DB >> 24671219

Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice.

Chengxin Sun1, Yan Chen, Xinzhi Li, Guihua Tai, Yuying Fan, Yifa Zhou.   

Abstract

Neutral (WGPN) and acidic (WGPA) polysaccharides were fractionated from ginseng polysaccharide. WGPN and WGPA decreased fasting blood glucose by different manners of administration. Intra-gastric administration of WGPA showed a marked hypoglycemic effect, which may be related to its anti-oxidative activity. The results indicated that WGPA may have anti-diabetic potential.

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Year:  2014        PMID： 24671219     DOI： 10.1039/c3fo60326a

Source DB:  PubMed          Journal:  Food Funct        ISSN： 2042-6496            Impact factor:   5.396


  14 in total

1.  Effect of white, red and black ginseng on physicochemical properties and ginsenosides.

Authors:  Yan Jin; Yeon-Ju Kim; Ji-Na Jeon; Chao Wang; Jin-Woo Min; Hae-Yong Noh; Deok-Chun Yang
Journal:  Plant Foods Hum Nutr       Date:  2015-06       Impact factor: 3.921

2.  Oral supplementation with ginseng polysaccharide promotes food intake in mice.

Authors:  Jiawen Wang; Yongxiang Li; Pei Luo; Yuhuang Chen; Qianyun Xi; Hanyu Wu; Weijie Zhao; Gang Shu; Songbo Wang; Ping Gao; Xiaotong Zhu; Yongliang Zhang; Qingyan Jiang; Lina Wang
Journal:  Brain Behav       Date:  2019-08-08       Impact factor: 2.708

3.  Characterization and Antioxidant Activity Determination of Neutral and Acidic Polysaccharides from Panax Ginseng C. A. Meyer.

Authors:  Hyung Min Kim; Yanxue Song; Gyu Hwan Hyun; Nguyen Phuoc Long; Jeong Hill Park; Yves S Y Hsieh; Sung Won Kwon
Journal:  Molecules       Date:  2020-02-12       Impact factor: 4.411

Review 4.  Advances in Mechanism Research on Polygonatum in Prevention and Treatment of Diabetes.

Authors:  Shuang Liu; Qiao-Jun Jia; Yi-Qing Peng; Ting-Hui Feng; Shu-Ting Hu; Juan-E Dong; Zong-Suo Liang
Journal:  Front Pharmacol       Date:  2022-02-08       Impact factor: 5.810

Review 5.  Clinical potentials of ginseng polysaccharide for treating gestational diabetes mellitus.

Authors:  Xuan-Yin Zhao; Fang Zhang; Wei Pan; Yi-Fang Yang; Xiao-Ya Jiang
Journal:  World J Clin Cases       Date:  2021-07-06       Impact factor: 1.337

Review 6.  Network Pharmacology Studies on the Bioactive Compounds and Action Mechanisms of Natural Products for the Treatment of Diabetes Mellitus: A Review.

Authors:  Weiwei Li; Guoqi Yuan; Yuxiang Pan; Cong Wang; Haixia Chen
Journal:  Front Pharmacol       Date:  2017-02-23       Impact factor: 5.810

7.  Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients.

Authors:  Mansour Alsharidah; Metab Algeffari; Abdel-Moneim Hafez Abdel-Moneim; Mohamed Faisal Lutfi; Haila Alshelowi
Journal:  Saudi Pharm J       Date:  2017-11-14       Impact factor: 4.330

8.  Panax ginseng Polysaccharide Protected H9c2 Cardiomyocyte From Hypoxia/Reoxygenation Injury Through Regulating Mitochondrial Metabolism and RISK Pathway.

Authors:  Yi-Han Zuo; Quan-Bin Han; Geng-Ting Dong; Rui-Qi Yue; Xue-Cong Ren; Jian-Xin Liu; Liang Liu; Pei Luo; Hua Zhou
Journal:  Front Physiol       Date:  2018-06-15       Impact factor: 4.566

Review 9.  Review of Ginseng Anti-Diabetic Studies.

Authors:  Wei Chen; Prabhu Balan; David G Popovich
Journal:  Molecules       Date:  2019-12-09       Impact factor: 4.411

Review 10.  A review of the immunomodulatory activities of polysaccharides isolated from Panax species.

Authors:  Yeye Hu; Yang He; Zhiqiang Niu; Ting Shen; Ji Zhang; Xinfeng Wang; Weicheng Hu; Jae Youl Cho
Journal:  J Ginseng Res       Date:  2021-06-04       Impact factor: 6.060
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