Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Whole-genome sequencing in newborn screening programs.

Literature DB >> 24670681

Whole-genome sequencing in newborn screening programs.

Bartha M Knoppers¹, Karine Sénécal, Pascal Borry, Denise Avard.

Abstract

The availability of whole-genome sequencing (WGS) is likely to change the practice of population screening programs such as newborn screening (NBS). This Commentary raises key ethical, legal, and social issues surrounding WGS in NBS and suggests a need for deliberation regarding the policy challenges of introducing sequencing in such programs. Any change in the goals of NBS programs should be discussed carefully and should represent the best interests of the child.

Entities: Disease Species

Mesh：

Year: 2014 PMID： 24670681 DOI： 10.1126/scitranslmed.3008494

Source DB: PubMed Journal: Sci Transl Med ISSN： 1946-6234 Impact factor: 17.956

Keyword Cloud
Cited

32 in total

Review 1. Population genetic testing for cancer susceptibility: founder mutations to genomes.

Authors: William D Foulkes; Bartha Maria Knoppers; Clare Turnbull
Journal: Nat Rev Clin Oncol Date: 2015-10-20 Impact factor: 66.675

Review 2. Return of genetic testing results in the era of whole-genome sequencing.

Authors: Bartha Maria Knoppers; Ma'n H Zawati; Karine Sénécal
Journal: Nat Rev Genet Date: 2015-08-04 Impact factor: 53.242

3. Genomic analysis in the clinic: benefits and challenges for health care professionals and patients in Brazil.

Authors: Patrícia Ashton-Prolla; José Roberto Goldim; Filippo Pinto E Vairo; Ursula da Silveira Matte; Jorge Sequeiros
Journal: J Community Genet Date: 2015-06-04

4. Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.

Authors: Susan M Wolf; Wylie Burke; Barbara A Koenig
Journal: J Law Med Ethics Date: 2015 Impact factor: 1.718

Whole-genome sequencing in newborn screening programs.

Review 1. Population genetic testing for cancer susceptibility: founder mutations to genomes.

Review 2. Return of genetic testing results in the era of whole-genome sequencing.

3. Genomic analysis in the clinic: benefits and challenges for health care professionals and patients in Brazil.

4. Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.

Review 5. Newborn screening: adapting to advancements in whole-genome sequencing.

Review 6. Next-Generation Sequencing and the Return of Results.

Review 7. Management and return of incidental genomic findings in clinical trials.

8. Genetics professionals' opinions of whole-genome sequencing in the newborn period.

9. Psychiatric Genetics in Child Custody Proceedings: Ethical, Legal, and Social Issues.

Review 10. Behavioral Genetics in Criminal and Civil Courts.