Literature DB >> 24664183

Bioorthogonal site-specific labeling of the 5'-cap structure in eukaryotic mRNAs.

Josephin Marie Holstein1, Daniela Schulz, Andrea Rentmeister.   

Abstract

We present a chemo-enzymatic approach for site-specific labeling of 5'-capped RNAs based on bioorthogonal chemistry. A trimethylguanosine synthase was engineered to transfer a terminal azido moiety to the 5'-cap which could be further modified using strain-promoted azide-alkyne cycloaddition (SPAAC).

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Year:  2014        PMID： 24664183     DOI： 10.1039/c4cc01549e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  22 in total

1.  mRNAs biotinylated within the 5' cap and protected against decapping: new tools to capture RNA-protein complexes.

Authors:  Sylwia Bednarek; Vanesa Madan; Pawel J Sikorski; Ralf Bartenschlager; Joanna Kowalska; Jacek Jemielity
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-11-05       Impact factor: 6.237

2.  Intermolecular 'cross-torque': the N4-cytosine propargyl residue is rotated to the 'CH'-edge as a result of Watson-Crick interaction.

Authors:  Olwen Domingo; Isabell Hellmuth; Andres Jäschke; Christoph Kreutz; Mark Helm
Journal:  Nucleic Acids Res       Date:  2015-04-30       Impact factor: 16.971

3.  Synthesis of S-Adenosyl-L-Methionine Analogs with Extended Transferable Groups for Methyltransferase-Directed Labeling of DNA and RNA.

Authors:  Viktoras Masevičius; Milda Nainytė; Saulius Klimašauskas
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2016-03-01

Review 4.  Translational control of gene function through optically regulated nucleic acids.

Authors:  Kristie E Darrah; Alexander Deiters
Journal:  Chem Soc Rev       Date:  2021-11-29       Impact factor: 54.564

Review 5.  Covalent labeling of nucleic acids.

Authors:  Nils Klöcker; Florian P Weissenboeck; Andrea Rentmeister
Journal:  Chem Soc Rev       Date:  2020-10-21       Impact factor: 54.564

6.  Nucleoside-modified AdoMet analogues for differential methyltransferase targeting.

Authors:  Nicolas V Cornelissen; Freideriki Michailidou; Fabian Muttach; Kristina Rau; Andrea Rentmeister
Journal:  Chem Commun (Camb)       Date:  2020-01-23       Impact factor: 6.222

7.  Vinyluridine as a Versatile Chemoselective Handle for the Post-transcriptional Chemical Functionalization of RNA.

Authors:  Jerrin Thomas George; Seergazhi G Srivatsan
Journal:  Bioconjug Chem       Date:  2017-04-26       Impact factor: 4.774

Review 8.  Enzyme-mediated bioorthogonal technologies: catalysts, chemoselective reactions and recent methyltransferase applications.

Authors:  Elnaz Jalali; Jon S Thorson
Journal:  Curr Opin Biotechnol       Date:  2021-04-24       Impact factor: 10.279

Review 9.  Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA.

Authors:  Miglė Tomkuvienė; Milda Mickutė; Giedrius Vilkaitis; Saulius Klimašauskas
Journal:  Curr Opin Biotechnol       Date:  2018-10-06       Impact factor: 9.740

10.  Visible-Light Removable Photocaging Groups Accepted by MjMAT Variant: Structural Basis and Compatibility with DNA and RNA Methyltransferases.

Authors:  Aileen Peters; Eric Herrmann; Nicolas V Cornelissen; Nils Klöcker; Daniel Kümmel; Andrea Rentmeister
Journal:  Chembiochem       Date:  2021-10-25       Impact factor: 3.461
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