| Literature DB >> 24659472 |
Martin Klebes1, Christin Ulrich1, Franziska Kluschke1, Alexa Patzelt1, Staffan Vandersee1, Heike Richter1, Adrienne Bob1, Johanna von Hutten1, Jorien T Krediet1, Axel Kramer1, Jürgen Lademann2, Bernhard Lange-Asschenfeld3,4.
Abstract
Potential antimicrobial effects of sequential applications of tissue-tolerable plasma (TTP) and the conventional liquid antiseptic octenidine dihydrochloride (ODC) were investigated. 34 patients with chronic leg ulcers were treated with TTP, ODC or a combination of both. The bacterial colonization was measured semi-quantitatively before and immediately after treatment and changes in the microbial strains' compositions before and after antiseptic treatments were analyzed. All antiseptic procedures reduced the bacterial counts significantly. The sequential application of TTP and ODC displayed the highest antimicrobial efficacy. Me combined use of TTP and conventional antiseptics might represent the most efficient strategy for antiseptic treatment of chronic wounds.Entities:
Keywords: antiseptic efficacy; chronic wounds; octenidine dihydrochloride (ODC); tissue tolerable plasma (TTP); wound disinfection
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Year: 2014 PMID： 24659472 DOI： 10.1002/jbio.201400007
Source DB: PubMed Journal: J Biophotonics ISSN： 1864-063X Impact factor: 3.207