Literature DB >> 24656040

NLRC3 puts the brakes on STING.

Matthew S J Mangan1, Eicke Latz2.   

Abstract

NOD-like receptors (NLRs) are increasingly implicated in regulating pathogen-sensing pathways. In this issue of Immunity, Zhang et al. (2014) describe a role for NLRC3 in regulating STING and the inflammatory response to cytosolic DNA.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24656040      PMCID： PMC4047561          DOI： 10.1016/j.immuni.2014.02.007

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  10 in total

1.  Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing.

Authors:  Nadine Gehrke; Christina Mertens; Thomas Zillinger; Jörg Wenzel; Tobias Bald; Sabine Zahn; Thomas Tüting; Gunther Hartmann; Winfried Barchet
Journal:  Immunity       Date:  2013-08-29       Impact factor: 31.745

2.  NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.

Authors:  Lu Zhang; Jinyao Mo; Karen V Swanson; Haitao Wen; Alex Petrucelli; Sean M Gregory; Zhigang Zhang; Monika Schneider; Yan Jiang; Katherine A Fitzgerald; Songying Ouyang; Zhi-Jie Liu; Blossom Damania; Hong-Bing Shu; Joseph A Duncan; Jenny P-Y Ting
Journal:  Immunity       Date:  2014-02-20       Impact factor: 31.745

Review 3.  Activation and regulation of the inflammasomes.

Authors:  Eicke Latz; T Sam Xiao; Andrea Stutz
Journal:  Nat Rev Immunol       Date:  2013-06       Impact factor: 53.106

Review 4.  STING-dependent cytosolic DNA sensing pathways.

Authors:  Glen N Barber
Journal:  Trends Immunol       Date:  2013-12-02       Impact factor: 16.687

5.  STING manifests self DNA-dependent inflammatory disease.

Authors:  Jeonghyun Ahn; Delia Gutman; Shinobu Saijo; Glen N Barber
Journal:  Proc Natl Acad Sci U S A       Date:  2012-11-06       Impact factor: 11.205

6.  NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.

Authors:  Eran Elinav; Till Strowig; Andrew L Kau; Jorge Henao-Mejia; Christoph A Thaiss; Carmen J Booth; David R Peaper; John Bertin; Stephanie C Eisenbarth; Jeffrey I Gordon; Richard A Flavell
Journal:  Cell       Date:  2011-05-12       Impact factor: 41.582

7.  NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens.

Authors:  Paras K Anand; R K Subbarao Malireddi; John R Lukens; Peter Vogel; John Bertin; Mohamed Lamkanfi; Thirumala-Devi Kanneganti
Journal:  Nature       Date:  2012-08-16       Impact factor: 49.962

8.  The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.

Authors:  Monika Schneider; Albert G Zimmermann; Reid A Roberts; Lu Zhang; Karen V Swanson; Haitao Wen; Beckley K Davis; Irving C Allen; Eda K Holl; Zhengmao Ye; Adeeb H Rahman; Brian J Conti; Timothy K Eitas; Beverly H Koller; Jenny P-Y Ting
Journal:  Nat Immunol       Date:  2012-08-05       Impact factor: 25.606

9.  Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection.

Authors:  Md Hasan Zaki; Si Ming Man; Peter Vogel; Mohamed Lamkanfi; Thirumala-Devi Kanneganti
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-17       Impact factor: 11.205

Review 10.  Unsolved Mysteries in NLR Biology.

Authors:  Christopher Lupfer; Thirumala-Devi Kanneganti
Journal:  Front Immunol       Date:  2013-09-17       Impact factor: 7.561
  10 in total
  5 in total

Review 1.  STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?

Authors:  Henrique Lemos; Lei Huang; Tracy McGaha; Andrew L Mellor
Journal:  Expert Rev Clin Immunol       Date:  2014-12-18       Impact factor: 4.473

Review 2.  NOD-like receptor(s) and host immune responses with Pseudomonas aeruginosa infection.

Authors:  Alaa Alhazmi
Journal:  Inflamm Res       Date:  2018-01-20       Impact factor: 4.575

Review 3.  Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure.

Authors:  Sheryl Coutermarsh-Ott; Kristin Eden; Irving Coy Allen
Journal:  J Gen Virol       Date:  2016-01-13       Impact factor: 3.891

Review 4.  STING modulators: Predictive significance in drug discovery.

Authors:  Xiangling Cui; Rongyu Zhang; Shan Cen; Jinming Zhou
Journal:  Eur J Med Chem       Date:  2019-08-08       Impact factor: 6.514

Review 5.  Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy.

Authors:  Min Zhang; Yan Zou; Xujun Zhou; Jinming Zhou
Journal:  Front Immunol       Date:  2022-09-12       Impact factor: 8.786
  5 in total

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