Literature DB >> 24649998

Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).

Vural Ozdemir1, Laszlo Endrenyi, Sükrü Aynacıoğlu, Nicola Luigi Bragazzi, Collet Dandara, Edward S Dove, Lynnette R Ferguson, Christy Jo Geraci, Ernst Hafen, Belgin Eroğlu Kesim, Eugene Kolker, Edmund J D Lee, Adrian Llerena, Muradiye Nacak, Kazutaka Shimoda, Toshiyuki Someya, Sanjeeva Srivastava, Brian Tomlinson, Effy Vayena, Louise Warnich, Umit Yaşar.   

Abstract

This article announces the recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine by the Pacific Rim Association for Clinical Pharmacogenetics (PRACP): Bernard Lerer, professor of psychiatry and director of the Biological Psychiatry Laboratory, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. The Werner Kalow Responsible Innovation Prize is given to an exceptional interdisciplinary scholar who has made highly innovative and enduring contributions to global omics science and personalized medicine, with both vertical and horizontal (transdisciplinary) impacts. The prize is established in memory of a beloved colleague, mentor, and friend, the late Professor Werner Kalow, who cultivated the idea and practice of pharmacogenetics in modern therapeutics commencing in the 1950s. PRACP, the prize's sponsor, is one of the longest standing learned societies in the Asia-Pacific region, and was founded by Kalow and colleagues more than two decades ago in the then-emerging field of pharmacogenetics. In announcing this inaugural prize and its winner, we seek to highlight the works of prize winner, Professor Lerer. Additionally, we contextualize the significance of the prize by recalling the life and works of Professor Kalow and providing a brief socio-technical history of the rise of pharmacogenetics and personalized medicine as a veritable form of 21(st) century scientific practice. The article also fills a void in previous social science analyses of pharmacogenetics, by bringing to the fore the works of Kalow from 1995 to 2008, when he presciently noted the rise of yet another field of postgenomics inquiry--pharmacoepigenetics--that railed against genetic determinism and underscored the temporal and spatial plasticity of genetic components of drug response, with invention of the repeated drug administration (RDA) method that estimates the dynamic heritabilities of drug response. The prize goes a long way to cultivate transgenerational capacity and broader cognizance of the concept and practice of responsible innovation as an important criterion of 21(st) century omics science and personalized medicine. A new call is presently in place for the 2016 PRACP Werner Kalow prize. Nominations can be made in support of an exceptional individual interdisciplinary scholar, or alternatively, an entire research team, from any region in the world with a record of highly innovative contributions to global omics science and/or personalized medicine, in the spirit of responsible innovation. The application process is straightforward, requiring a signed, 1500-word nomination letter (by the applicant or sponsor) submitted not later than May 31, 2015.

Mesh:

Year:  2014        PMID: 24649998      PMCID: PMC3976589          DOI: 10.1089/omi.2014.0029

Source DB:  PubMed          Journal:  OMICS        ISSN: 1536-2310


  44 in total

1.  Lymphoblast and brain expression of AHI1 and the novel primate-specific gene, C6orf217, in schizophrenia and bipolar disorder.

Authors:  Alexandra Slonimsky; Itzchak Levy; Yoav Kohn; Amihai Rigbi; Edna Ben-Asher; Doron Lancet; Galila Agam; Bernard Lerer
Journal:  Schizophr Res       Date:  2010-05-08       Impact factor: 4.939

2.  How can we help? From "sociology in" to "sociology of" bioethics.

Authors:  Raymond De Vries
Journal:  J Law Med Ethics       Date:  2004       Impact factor: 1.718

3.  Technologies of humility.

Authors:  Sheila Jasanoff
Journal:  Nature       Date:  2007-11-01       Impact factor: 49.962

Review 4.  Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy.

Authors:  Vural Özdemir; Eugene Kolker; Peter J Hotez; Sophie Mohin; Barbara Prainsack; Brian Wynne; Effy Vayena; Yavuz Coşkun; Türkay Dereli; Farah Huzair; Alexander Borda-Rodriguez; Nicola Luigi Bragazzi; Jack Faris; Raj Ramesar; Ambroise Wonkam; Collet Dandara; Bipin Nair; Adrián Llerena; Koray Kılıç; Rekha Jain; Panga Jaipal Reddy; Kishore Gollapalli; Sanjeeva Srivastava; Ilona Kickbusch
Journal:  OMICS       Date:  2014-01

5.  All the post-genomic world is a stage: the actors and narrators required for translating pharmacogenomics into public health.

Authors:  Edward S Dove; Vural Ozdemir
Journal:  Per Med       Date:  2013-05-01       Impact factor: 2.512

6.  Clinical strategies for evaluating ECT mechanisms--pharmacological, biochemical and psychophysiological approaches.

Authors:  B Lerer; N Sitaram
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  1983       Impact factor: 5.067

7.  Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms: towards addressing the missing heritability in pharmacogenetic phenotypes?

Authors:  Janine E Micheli; Leslie W Chinn; Sarah B Shugarts; Ashish Patel; Jeffrey N Martin; David R Bangsberg; Deanna L Kroetz
Journal:  Pharmacogenet Genomics       Date:  2013-11       Impact factor: 2.089

8.  Why do young women smoke? IV. Role of genetic variation in the dopamine transporter and lifetime traumatic experience.

Authors:  Ronnen H Segman; Kyra Kanyas; Osnat Karni; Elad Lerer; Tanya Goltser-Dubner; Vera Pavlov; Bernard Lerer
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2007-06-05       Impact factor: 3.568

9.  Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism.

Authors:  Bernard Lerer; Ronnen H Segman; Heiner Fangerau; Ann K Daly; Vincenzo S Basile; Roberto Cavallaro; Harald N Aschauer; Robin G McCreadie; Stephanie Ohlraun; Nicol Ferrier; Mario Masellis; Massimiliano Verga; Joachim Scharfetter; Marcella Rietschel; Roger Lovlie; Uriel Heresco Levy; Herbert Y Meltzer; James L Kennedy; Vidar M Steen; Fabio Macciardi
Journal:  Neuropsychopharmacology       Date:  2002-07       Impact factor: 7.853

10.  Situating Nutri-Ethics at the Junction of Nutrigenomics and Nutriproteomics in Postgenomics Medicine.

Authors:  Nicola Luigi Bragazzi
Journal:  Curr Pharmacogenomics Person Med       Date:  2013-06
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  6 in total

1.  OMICS 2.0: An Accelerator for Global Science, Systems Medicine and Responsible Innovation.

Authors:  Vural Özdemir
Journal:  OMICS       Date:  2015-10

Review 2.  Personalized medicine beyond genomics: alternative futures in big data-proteomics, environtome and the social proteome.

Authors:  Vural Özdemir; Edward S Dove; Ulvi K Gürsoy; Semra Şardaş; Arif Yıldırım; Şenay Görücü Yılmaz; I Ömer Barlas; Kıvanç Güngör; Alper Mete; Sanjeeva Srivastava
Journal:  J Neural Transm (Vienna)       Date:  2015-12-08       Impact factor: 3.575

3.  Evaluation of Nine Consensus Indices in Delphi Foresight Research and Their Dependency on Delphi Survey Characteristics: A Simulation Study and Debate on Delphi Design and Interpretation.

Authors:  Stanislav Birko; Edward S Dove; Vural Özdemir
Journal:  PLoS One       Date:  2015-08-13       Impact factor: 3.240

4.  A Delphi Technology Foresight Study: Mapping Social Construction of Scientific Evidence on Metagenomics Tests for Water Safety.

Authors:  Stanislav Birko; Edward S Dove; Vural Özdemir
Journal:  PLoS One       Date:  2015-06-11       Impact factor: 3.240

5.  Using current data to define new approach in age related macular degeneration: need to accelerate translational research.

Authors:  Akshay Anand; Kaushal Sharma; Wei Chen; Neel Kamal Sharma
Journal:  Curr Genomics       Date:  2014-08       Impact factor: 2.236

6.  Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area.

Authors:  Aihua Li; David Meyre
Journal:  Curr Psychiatry Rev       Date:  2014-05
  6 in total

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