Literature DB >> 2464981

Extent of lymph node dissection in melanoma of the trunk or lower extremity.

D G Coit1, M F Brennan.   

Abstract

The extent of lymph node dissection necessary to optimize survival and minimize local recurrence in patients with melanoma of the trunk or lower extremity is not well defined. We reviewed the records of 420 patients undergoing superficial or combined superficial and deep groin dissection for melanoma. Prognosis depended on the extent of lymph node involvement rather than the extent of surgery performed. Node-positive patients undergoing elective lymph node dissection had an improved survival over those undergoing therapeutic lymph node dissection. In no subgroup of patients was more extensive lymphadenectomy associated with significant improvement in survival or alteration in pattern of recurrence. Dissection of the deep pelvic nodes in patients with melanoma appears to be of more prognostic than therapeutic value.

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Year:  1989        PMID: 2464981     DOI: 10.1001/archsurg.1989.01410020032004

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  14 in total

1.  Robotic-Assisted Transperitoneal Pelvic Lymphadenectomy for Metastatic Melanoma: Early Outcomes Compared with Open Pelvic Lymphadenectomy.

Authors:  Lesly A Dossett; Nicholas B Castner; Julio M Pow-Sang; Andrea M Abbott; Vernon K Sondak; Amod A Sarnaik; Jonathan S Zager
Journal:  J Am Coll Surg       Date:  2016-01-14       Impact factor: 6.113

2.  Preoperative ultrasound is not useful for identifying nodal metastasis in melanoma patients undergoing sentinel node biopsy: preoperative ultrasound in clinically node-negative melanoma.

Authors:  Christy Y Chai; Jonathan S Zager; Margaret M Szabunio; Suroosh S Marzban; Alec Chau; Robert M Rossi; Vernon K Sondak
Journal:  Ann Surg Oncol       Date:  2011-12-23       Impact factor: 5.344

3.  Regional control and morbidity after superficial groin dissection in melanoma.

Authors:  Amber L Shada; Craig L Slingluff
Journal:  Ann Surg Oncol       Date:  2010-12-07       Impact factor: 5.344

4.  Inguinopelvic lymphadenectomy following positive inguinal sentinel lymph node biopsy in melanoma: true frequency of synchronous pelvic metastases.

Authors:  Carrie K Chu; Keith A Delman; Grant W Carlson; Andrea C Hestley; Douglas R Murray
Journal:  Ann Surg Oncol       Date:  2011-05-04       Impact factor: 5.344

5.  Prognostic factors in patients with melanoma metastatic to axillary or inguinal lymph nodes. A multivariate analysis.

Authors:  D G Coit; A Rogatko; M F Brennan
Journal:  Ann Surg       Date:  1991-11       Impact factor: 12.969

6.  [Inguinal recurrence after therapeutic lymphadenectomy in malignant melanoma].

Authors:  L Kretschmer; C Lautenschläger; K P Preusser; H Fiedler
Journal:  Langenbecks Arch Chir       Date:  1993

7.  [Axillary recurrence after lymph node excision in malignant melanoma].

Authors:  L Kretschmer; C Lautenschläger; K P Preusser; H Fiedler; I Hetschko
Journal:  Langenbecks Arch Chir       Date:  1993

Review 8.  Intermediate- and high-risk melanoma.

Authors:  Sanjiv S Agarwala
Journal:  Curr Treat Options Oncol       Date:  2002-06

9.  Axillary dissection in melanoma. Prognostic variables in node-positive patients.

Authors:  R G Bevilacqua; D G Coit; A Rogatko; R N Younes; M F Brennan
Journal:  Ann Surg       Date:  1990-08       Impact factor: 12.969

10.  Superficial and deep lymph node dissection for stage III cutaneous melanoma: clinical outcome and prognostic factors.

Authors:  Nicola Mozzillo; Corrado Caracò; Ugo Marone; Gianluca Di Monta; Anna Crispo; Gerardo Botti; Maurizio Montella; Paolo Antonio Ascierto
Journal:  World J Surg Oncol       Date:  2013-02-04       Impact factor: 2.754

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