BACKGROUND: The Bahcesehir Breast Cancer Screening Project is the first organized population based breast cancer mammographic screening project in Turkey. The objective of this prospective observational study was to demonstrate the feasibility of a screening program in a developing country and to determine the appropriate age (40 or 50 years old) to start with screening in Turkish women. MATERIALS AND METHODS: Between January 2009 to December 2010, a total of 3,758 women aged 40-69 years were recruited in this prospective study. Screening was conducted biannually, and five rounds were planned. After clinical breast examination (CBE), two-view mammograms were obtained. True positivity, false positivity, positive predictive values (PPV) according to ACR, cancer detection rate, minimal cancer detection rate, axillary node positivity and recall rate were calculated. Breast ultrasound and biopsy were performed in suspicious cases. RESULTS: Breast biopsy was performed in 55 patients, and 18 cancers were detected in the first round. The overall cancer detection rate was 4.8 per 1,000 women. Most of the screened women (54%) and detected cancers (56%) were in women aged 40- 49. Ductal carcinoma in situ (DCIS) and stage I cancer and axillary node positivity rates were 22%, 61%, and 16.6%, respectively. The positive predictivity for biopsy was 32.7%, whereas the overall recall rate was 18.4 %. CONCLUSIONS: Preliminary results of the study suggest that population based organized screening are feasible and age of onset of mammographic screening should be 40 years in Turkey.
BACKGROUND: The Bahcesehir Breast Cancer Screening Project is the first organized population based breast cancer mammographic screening project in Turkey. The objective of this prospective observational study was to demonstrate the feasibility of a screening program in a developing country and to determine the appropriate age (40 or 50 years old) to start with screening in Turkish women. MATERIALS AND METHODS: Between January 2009 to December 2010, a total of 3,758 women aged 40-69 years were recruited in this prospective study. Screening was conducted biannually, and five rounds were planned. After clinical breast examination (CBE), two-view mammograms were obtained. True positivity, false positivity, positive predictive values (PPV) according to ACR, cancer detection rate, minimal cancer detection rate, axillary node positivity and recall rate were calculated. Breast ultrasound and biopsy were performed in suspicious cases. RESULTS: Breast biopsy was performed in 55 patients, and 18 cancers were detected in the first round. The overall cancer detection rate was 4.8 per 1,000 women. Most of the screened women (54%) and detected cancers (56%) were in women aged 40- 49. Ductal carcinoma in situ (DCIS) and stage I cancer and axillary node positivity rates were 22%, 61%, and 16.6%, respectively. The positive predictivity for biopsy was 32.7%, whereas the overall recall rate was 18.4 %. CONCLUSIONS: Preliminary results of the study suggest that population based organized screening are feasible and age of onset of mammographic screening should be 40 years in Turkey.
Authors: Valerie A McCormack; Anya Burton; Isabel dos-Santos-Silva; John H Hipwell; Caroline Dickens; Dorria Salem; Rasha Kamal; Mikael Hartman; Charmaine Pei Ling Lee; Kee-Seng Chia; Vahit Ozmen; Mustafa Erkin Aribal; Anath Arzee Flugelman; Martín Lajous; Ruy Lopez-Riduara; Megan Rice; Isabelle Romieu; Giske Ursin; Samera Qureshi; Huiyan Ma; Eunjung Lee; Carla H van Gils; Johanna O P Wanders; Sudhir Vinayak; Rose Ndumia; Steve Allen; Sarah Vinnicombe; Sue Moss; Jong Won Lee; Jisun Kim; Ana Pereira; Maria Luisa Garmendia; Reza Sirous; Mehri Sirous; Beata Peplonska; Agnieszka Bukowska; Rulla M Tamimi; Kimberly Bertrand; Chisato Nagata; Ava Kwong; Celine Vachon; Christopher Scott; Beatriz Perez-Gomez; Marina Pollan; Gertraud Maskarinec; Graham Giles; John Hopper; Jennifer Stone; Nadia Rajaram; Soo-Hwang Teo; Shivaani Mariapun; Martin J Yaffe; Joachim Schüz; Anna M Chiarelli; Linda Linton; Norman F Boyd Journal: Cancer Epidemiol Date: 2015-12-24 Impact factor: 2.984
Authors: Vahit Özmen; Nergiz Dağoğlu; İsmet Dede; Adem Akçakaya; Mustafa Kerem; Fatih Göksel; Enver Özgür; Emel Başkan; Mustafa Yaylacı; Adil Ceydeli; Meltem Baykara; Huriye Şenay Kızıltan; Şeref Kömürcü; Mahmut Gümüş; H Mehmet Türk; Recep Demirhan; Ali Akgün; Naim Kadoglou; Emre Yatman; Cem Cüneyt Elbi; Seza Güleç; Atilla Soran; Ahmet Özet; Fahrettin Keleştimur Journal: J Breast Health Date: 2016-01-01
Authors: Anya Burton; Graham Byrnes; Jennifer Stone; Rulla M Tamimi; John Heine; Celine Vachon; Vahit Ozmen; Ana Pereira; Maria Luisa Garmendia; Christopher Scott; John H Hipwell; Caroline Dickens; Joachim Schüz; Mustafa Erkin Aribal; Kimberly Bertrand; Ava Kwong; Graham G Giles; John Hopper; Beatriz Pérez Gómez; Marina Pollán; Soo-Hwang Teo; Shivaani Mariapun; Nur Aishah Mohd Taib; Martín Lajous; Ruy Lopez-Riduara; Megan Rice; Isabelle Romieu; Anath Arzee Flugelman; Giske Ursin; Samera Qureshi; Huiyan Ma; Eunjung Lee; Reza Sirous; Mehri Sirous; Jong Won Lee; Jisun Kim; Dorria Salem; Rasha Kamal; Mikael Hartman; Hui Miao; Kee-Seng Chia; Chisato Nagata; Sudhir Vinayak; Rose Ndumia; Carla H van Gils; Johanna O P Wanders; Beata Peplonska; Agnieszka Bukowska; Steve Allen; Sarah Vinnicombe; Sue Moss; Anna M Chiarelli; Linda Linton; Gertraud Maskarinec; Martin J Yaffe; Norman F Boyd; Isabel Dos-Santos-Silva; Valerie A McCormack Journal: Breast Cancer Res Date: 2016-12-19 Impact factor: 6.466
Authors: René Aloísio da Costa Vieira; Gabriele Biller; Gilberto Uemura; Carlos Alberto Ruiz; Maria Paula Curado Journal: Clinics (Sao Paulo) Date: 2017-04 Impact factor: 2.365