Literature DB >> 2463634

Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.

H Yagita1, T Nakamura, H Karasuyama, K Okumura.   

Abstract

Monoclonal antibodies specific for the murine CD2 antigen were identified by an efficient screening method utilizing murine CD2 cDNA transfectants. An unexpected expression of CD2 on murine B cells was revealed by immunofluorescence and immunoprecipitation studies with these monoclonal antibodies and by RNA blot analysis for the murine CD2 transcript.

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Year:  1989        PMID： 2463634      PMCID： PMC286529          DOI： 10.1073/pnas.86.2.645

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  61 in total

1.  Selective inhibition of interleukin 2 gene function following thymocyte antigen/major histocompatibility complex receptor crosslinking: possible thymic selection mechanism.

Authors:  D Ramarli; D A Fox; E L Reinherz
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

2.  Murine and human T11 (CD2) cDNA sequences suggest a common signal transduction mechanism.

Authors:  L K Clayton; P H Sayre; J Novotny; E L Reinherz
Journal:  Eur J Immunol       Date:  1987-09       Impact factor: 5.532

Review 3.  The structure of the CD4 and CD8 genes.

Authors:  D R Littman
Journal:  Annu Rev Immunol       Date:  1987       Impact factor: 28.527

4.  The T11 (CD2) molecule is functionally linked to the T3/Ti T cell receptor in the majority of T cells.

Authors:  J B Breitmeyer; J F Daley; H B Levine; S F Schlossman
Journal:  J Immunol       Date:  1987-11-01       Impact factor: 5.422

5.  Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation.

Authors:  B E Bierer; A Peterson; J Barbosa; B Seed; S J Burakoff
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

6.  An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2.

Authors:  B Seed
Journal:  Nature       Date:  1987 Oct 29-Nov 4       Impact factor: 49.962

7.  Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3.

Authors:  Y Takai; M L Reed; S J Burakoff; S H Herrmann
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

8.  Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation.

Authors:  G Tiefenthaler; T Hünig; M L Dustin; T A Springer; S C Meuer
Journal:  Eur J Immunol       Date:  1987-12       Impact factor: 5.532

9.  Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11.

Authors:  H Yagita; K Okumura; H Nakauchi
Journal:  J Immunol       Date:  1988-02-15       Impact factor: 5.422

10.  Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein.

Authors:  B P Wallner; A Z Frey; R Tizard; R J Mattaliano; C Hession; M E Sanders; M L Dustin; T A Springer
Journal:  J Exp Med       Date:  1987-10-01       Impact factor: 14.307
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  35 in total

1.  The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

Authors:  D Vremec; M Zorbas; R Scollay; D J Saunders; C F Ardavin; L Wu; K Shortman
Journal:  J Exp Med       Date:  1992-07-01       Impact factor: 14.307

2.  A feline CD2 homologue interacts with human red blood cells.

Authors:  Masayuki Shimojima; Yorihiro Nishimura; Takayuki Miyazawa; Kentaro Kato; Kazuya Nakamura; Yoshihiro Izumiya; Hiroomi Akashi; Yukinobu Tohya
Journal:  Immunology       Date:  2002-03       Impact factor: 7.397

3.  A multimeric form of soluble recombinant sheep LFA-3 (CD58) inhibits human T-cell proliferation.

Authors:  K Yamashita; C R Parish; H S Warren; L C Harrison
Journal:  Immunology       Date:  1997-09       Impact factor: 7.397

4.  Human CD2 is functional in CD2 transgenic mice.

Authors:  E Monostori; G Lang; D Kioussis; D A Cantrell; R Zamoyska; M H Brown; M J Crumpton
Journal:  Immunology       Date:  1991-11       Impact factor: 7.397

5.  Deletion analysis of the human CD2 gene locus control region in transgenic mice.

Authors:  G Lang; C Mamalaki; D Greenberg; N Yannoutsos; D Kioussis
Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971

6.  Production of multiple murine CD2 receptor constructs using the baculovirus expression vector and a rapid dot-blot assay.

Authors:  A J Kaplan; K D Chavin; L H Qin; H Yagita; J S Bromberg
Journal:  Immunol Res       Date:  1994       Impact factor: 2.829

7.  Combination anti-CD2 and anti-CD3 monoclonal antibodies induce tolerance while altering interleukin-2, interleukin-4, tumor necrosis factor, and transforming growth factor-beta production.

Authors:  K D Chavin; L Qin; J Lin; J E Woodward; P Baliga; J S Bromberg
Journal:  Ann Surg       Date:  1993-10       Impact factor: 12.969

8.  Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.

Authors:  H R Rodewald; K Awad; P Moingeon; L D'Adamio; D Rabinowitz; Y Shinkai; F W Alt; E L Reinherz
Journal:  J Exp Med       Date:  1993-04-01       Impact factor: 14.307

9.  Identification, by protein sequencing and gene transfection, of sgp-60 as the murine homologue of CD48.

Authors:  J G Cabrero; G J Freeman; W S Lane; H Reiser
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

10.  Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia.

Authors:  W P Lynch; S J Robertson; J L Portis
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103
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