| Literature DB >> 24633359 |
Masataka Narukawa1, Yasuka Toda, Tomoya Nakagita, Yukako Hayashi, Takumi Misaka.
Abstract
L-Theanine is a unique amino acid present in green tea. It elicits umami taste and has a considerable effect on tea taste and quality. We investigated L-theanine activity on the T1R1 + T1R3 umami taste receptor. L-Theanine activated T1R1 + T1R3-expressing cells and showed a synergistic response with inosine 5'-monophosphate. The site-directed mutagenesis analysis revealed that L-theanine binds to L-amino acid binding site in the Venus flytrap domain of T1R1. This study shows that L-theanine elicits an umami taste via T1R1 + T1R3.Entities:
Mesh：
Substances：
Year: 2014 PMID： 24633359 DOI： 10.1007/s00726-014-1713-3
Source DB: PubMed Journal: Amino Acids ISSN： 0939-4451 Impact factor: 3.520