Literature DB >> 24631681

Dynamic epigenetic responses to muscle contraction.

Morten Rasmussen1, Juleen R Zierath2, Romain Barrès3.   

Abstract

Skeletal muscle is a malleable organ that responds to a single acute exercise bout by inducing the expression of genes involved in structural, metabolic and functional adaptations. Several epigenetic mechanisms including histone H4 deacetylation and loss of promoter methylation have been implicated in modifying exercise-responsive gene expression. These transient changes suggest that epigenetic mechanisms are not restricted to early stages of human development but are broad dynamic controllers of genomic plasticity in response to environmental factors.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID: 24631681     DOI: 10.1016/j.drudis.2014.03.003

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  13 in total

Review 1.  Exercise attenuates the major hallmarks of aging.

Authors:  Nuria Garatachea; Helios Pareja-Galeano; Fabian Sanchis-Gomar; Alejandro Santos-Lozano; Carmen Fiuza-Luces; María Morán; Enzo Emanuele; Michael J Joyner; Alejandro Lucia
Journal:  Rejuvenation Res       Date:  2015-02       Impact factor: 4.663

Review 2.  Metabolic Flexibility in Health and Disease.

Authors:  Bret H Goodpaster; Lauren M Sparks
Journal:  Cell Metab       Date:  2017-05-02       Impact factor: 27.287

3.  Precision Physical Therapy: Exercise, the Epigenome, and the Heritability of Environmentally Modified Traits.

Authors:  Jessica R Woelfel; Shauna Dudley-Javoroski; Richard K Shields
Journal:  Phys Ther       Date:  2018-11-01

4.  Does metabosensitive afferent fibers activity differ from slow- and fast-twitch muscles?

Authors:  Guillaume Caron; Patrick Decherchi; Tanguy Marqueste
Journal:  Exp Brain Res       Date:  2015-05-21       Impact factor: 1.972

Review 5.  Impact of Exercise and Aging on Mitochondrial Homeostasis in Skeletal Muscle: Roles of ROS and Epigenetics.

Authors:  Jialin Li; Zhe Wang; Can Li; Yu Song; Yan Wang; Hai Bo; Yong Zhang
Journal:  Cells       Date:  2022-06-30       Impact factor: 7.666

6.  A necessary role of DNMT3A in endurance exercise by suppressing ALDH1L1-mediated oxidative stress.

Authors:  Sneha Damal Villivalam; Scott M Ebert; Hee Woong Lim; Jinse Kim; Dongjoo You; Byung Chul Jung; Hector H Palacios; Tabitha Tcheau; Christopher M Adams; Sona Kang
Journal:  EMBO J       Date:  2021-04-13       Impact factor: 11.598

7.  Metabolic Flexibility and Mechanical Efficiency in Women Over-60.

Authors:  Cristina Blasco-Lafarga; Jordi Monferrer-Marín; Ainoa Roldán; Pablo Monteagudo; Ivan Chulvi-Medrano
Journal:  Front Physiol       Date:  2022-04-06       Impact factor: 4.755

8.  Epigenetics: Its Understanding Is Crucial to a Sustainable Healthcare System.

Authors:  Michelle Thunders
Journal:  Healthcare (Basel)       Date:  2015-04-01

9.  Muscle Contraction Induces Acute Hydroxymethylation of the Exercise-Responsive Gene Nr4a3.

Authors:  Pattarawan Pattamaprapanont; Christian Garde; Odile Fabre; Romain Barrès
Journal:  Front Endocrinol (Lausanne)       Date:  2016-12-23       Impact factor: 5.555

Review 10.  The Combination of Physical Exercise with Muscle-Directed Antioxidants to Counteract Sarcopenia: A Biomedical Rationale for Pleiotropic Treatment with Creatine and Coenzyme Q10.

Authors:  Michele Guescini; Luca Tiano; Maria Luisa Genova; Emanuela Polidori; Sonia Silvestri; Patrik Orlando; Carmela Fimognari; Cinzia Calcabrini; Vilberto Stocchi; Piero Sestili
Journal:  Oxid Med Cell Longev       Date:  2017-09-20       Impact factor: 6.543

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