Chengcheng Zhu1, Umar Sadat2, Andrew J Patterson3, Zhongzhao Teng3, Jonathan H Gillard3, Martin J Graves3. 1. University Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK. Electronic address: cz254@cam.ac.uk. 2. Vascular Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK. 3. University Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK.
Abstract
OBJECTIVE: Development of a fast 3D high-resolution magnetic resonance imaging (MRI) protocol for improved carotid artery plaque imaging. METHODS: Two patients with carotid atherosclerosis disease underwent 3D high-resolution MRI which included time-of-flight and T1-weighted variable flip angle, fast-spin-echo (FSE) imaging, pre- and post-intravenous gadolinium-based contrast agent administration. RESULTS: Good quality images with intrinsic blood suppression were obtained pre- and post-contrast administration using a 3D FSE sequence. The plaque burden, lipid core volume, hemorrhage volume and fibrous cap thickness were well determined. CONCLUSIONS: 3D high-resolution MR imaging of carotid plaque using TOF and 3D FSE can achieve high isotropic resolution, large coverage, and excellent image quality within a short acquisition time.
OBJECTIVE: Development of a fast 3D high-resolution magnetic resonance imaging (MRI) protocol for improved carotid artery plaque imaging. METHODS: Two patients with carotid atherosclerosis disease underwent 3D high-resolution MRI which included time-of-flight and T1-weighted variable flip angle, fast-spin-echo (FSE) imaging, pre- and post-intravenous gadolinium-based contrast agent administration. RESULTS: Good quality images with intrinsic blood suppression were obtained pre- and post-contrast administration using a 3D FSE sequence. The plaque burden, lipid core volume, hemorrhage volume and fibrous cap thickness were well determined. CONCLUSIONS: 3D high-resolution MR imaging of carotid plaque using TOF and 3D FSE can achieve high isotropic resolution, large coverage, and excellent image quality within a short acquisition time.
Authors: Chengcheng Zhu; Henrik Haraldsson; Bing Tian; Karl Meisel; Nerissa Ko; Michael Lawton; John Grinstead; Sinyeob Ahn; Gerhard Laub; Christopher Hess; David Saloner Journal: MAGMA Date: 2016-03-05 Impact factor: 2.310
Authors: C Zhu; X Wang; L Eisenmenger; B Tian; Q Liu; A J Degnan; C Hess; D Saloner; J Lu Journal: AJNR Am J Neuroradiol Date: 2019-05-23 Impact factor: 3.825
Authors: Yan Wang; Florent Seguro; Evan Kao; Yue Zhang; Farshid Faraji; Chengcheng Zhu; Henrik Haraldsson; Michael Hope; David Saloner; Jing Liu Journal: Med Image Anal Date: 2017-05-19 Impact factor: 8.545