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Literature DB >> 24628401

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.

Christine M O'Brien¹, Elizabeth Vargis, Bibhash C Paria, Kelly A Bennett, Anita Mahadevan-Jansen, Jeff Reese.

Abstract

UNLABELLED: The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods.
CONCLUSION: Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities: CellLine Chemical Disease Gene Species

Keywords: Cervical remodelling; Cervix; Parturition; Pregnancy; Preterm birth

Mesh：

Year: 2014 PMID： 24628401 PMCID： PMC4048629 DOI： 10.1111/apa.12630

Source DB: PubMed Journal: Acta Paediatr ISSN： 0803-5253 Impact factor: 2.299

52 in total

Review 1. The epidemiology of preterm labor.

Authors: J N Robinson; J A Regan; E R Norwitz
Journal: Semin Perinatol Date: 2001-08 Impact factor: 3.300

2. Simultaneous fingerprint and high-wavenumber confocal Raman spectroscopy enhances early detection of cervical precancer in vivo.

Authors: Shiyamala Duraipandian; Wei Zheng; Joseph Ng; Jeffrey J H Low; A Ilancheran; Zhiwei Huang
Journal: Anal Chem Date: 2012-06-20 Impact factor: 6.986

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.

Review 1. The epidemiology of preterm labor.

2. Simultaneous fingerprint and high-wavenumber confocal Raman spectroscopy enhances early detection of cervical precancer in vivo.

Review 3. Dynamics of cervical remodeling during pregnancy and parturition: mechanisms and current concepts.

4. Effect of normal variations on disease classification of Raman spectra from cervical tissue.

5. The contribution of preterm birth to infant mortality rates in the United States.

6. Rate of sonographic cervical shortening and the risk of spontaneous preterm birth.

7. A study of the anisotropy and tension/compression behavior of human cervical tissue.

Review 8. Endoscopic screening and surveillance for Barrett's esophagus--clinical implications.

Review 9. Prediction and early detection of preterm labor.

10. Near-infrared Raman Microspectroscopy Detects High-risk Human Papillomaviruses.

Review 1. Clinical instrumentation and applications of Raman spectroscopy.

2. Development of a visually guided Raman spectroscopy probe for cervical assessment during pregnancy.

Review 3. New techniques in evaluation of the cervix.

4. In vivo Raman spectroscopy for biochemical monitoring of the human cervix throughout pregnancy.

5. In vivo Raman spectral analysis of impaired cervical remodeling in a mouse model of delayed parturition.

Review 6. Contributions to the dynamics of cervix remodeling prior to term and preterm birth.

7. Percentage fat fraction in magnetic resonance imaging: upgrading the osteoporosis-detecting parameter.