| Literature DB >> 24624324 |
Emmi Broenen1, Annelies Mavinkurve-Groothuis1, Karin Kamphuis-van Ulzen2, Roger Brüggemann3, Paul Verweij4, Adilia Warris5.
Abstract
The existing guidelines regarding the management of invasive pulmonary aspergillosis do not recommend screening of the extra-pulmonary sites. Due to the fact that the presence of central nervous system (CNS) aspergillosis will influence treatment decisions regarding which antifungal to use and the aimed target concentrations of azoles in plasma, to be informed about dissemination of the infection to the CNS is absolutely necessary. We demonstrate the need for a structured approach to screening of pediatric patients for CNS aspergillosis.Entities:
Keywords: Aspergillosis; Central nervous system; Pediatrics; Screening; Therapeutic drug monitoring; Voriconazole
Year: 2014 PMID: 24624324 PMCID: PMC3950533 DOI: 10.1016/j.mmcr.2014.02.001
Source DB: PubMed Journal: Med Mycol Case Rep ISSN: 2211-7539