Literature DB >> 2462369

Monoclonal antibody GB24 recognizes a trophoblast-lymphocyte cross-reactive antigen.

B L Hsi1, C J Yeh, P Fénichel, M Samson, C Grivaux.   

Abstract

GB24 is a mouse monoclonal antibody (IgG1) raised against human term placental microvilli. This antibody displayed pan-trophoblast reactivity pattern. In addition, GB24 recognized normal peripheral leukocytes and transformed cell lines (Daudi, HL-60, Jurkat, AV3, BeWo, HT-29) by using membrane immunofluorescence and flow cytometry. By SDS-polyacrylamide gel electrophoresis, this antibody immunoprecipitated two proteins of 62 kilodaltons (kDa) and 75 kDa from placental microvilli. Isoelectrofocusing analysis revealed that these two bands exhibited different isoelectric points: 4.7 for the 62 kDa protein, 4.6 and 4.4 for the two spots corresponding to the 75 kDa protein. Microvilli from different placentae revealed substantial differences regarding the intensity of the labeling of these two bands, suggesting that the antigens recognized by GB24 are probably allotypic.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2462369     DOI： 10.1111/j.1600-0897.1988.tb00228.x

Source DB:  PubMed          Journal:  Am J Reprod Immunol Microbiol        ISSN： 8755-8920


  12 in total

1.  Adenovirus type 11 uses CD46 as a cellular receptor.

Authors:  Anna Segerman; John P Atkinson; Marko Marttila; Veronica Dennerquist; Göran Wadell; Niklas Arnberg
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

2.  Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.

Authors:  Maria I Leite; Margaret Jones; Philipp Ströbel; Alexander Marx; Ralf Gold; Erik Niks; Jan J G M Verschuuren; Sonia Berrih-Aknin; Francesco Scaravilli; Aurea Canelhas; B Paul Morgan; Angela Vincent; Nick Willcox
Journal:  Am J Pathol       Date:  2007-08-03       Impact factor: 4.307

3.  Clinical isolates of measles virus use CD46 as a cellular receptor.

Authors:  M Manchester; D S Eto; A Valsamakis; P B Liton; R Fernandez-Muñoz; P A Rota; W J Bellini; D N Forthal; M B Oldstone
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

4.  High expression of the antigen recognized by the monoclonal antibody GB24 on human breast carcinomas: a preventive mechanism of malignant tumor cells against complement attack?

Authors:  P Hofman; B L Hsi; S Manie; P Fenichel; A Thyss; B Rossi
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

5.  Measles virus and C3 binding sites are distinct on membrane cofactor protein (CD46).

Authors:  M Manchester; A Valsamakis; R Kaufman; M K Liszewski; J Alvarez; J P Atkinson; D M Lublin; M B Oldstone
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

6.  Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus.

Authors:  M Manchester; M K Liszewski; J P Atkinson; M B Oldstone
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205

7.  The human cell-surface glycoproteins HuLy-m5, membrane co-factor protein (MCP) of the complement system, and trophoblast leucocyte-common (TLX) antigen, are CD46.

Authors:  D F Purcell; I F McKenzie; D M Lublin; P M Johnson; J P Atkinson; T J Oglesby; N J Deacon
Journal:  Immunology       Date:  1990-06       Impact factor: 7.397

8.  Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay.

Authors:  S W Cho; T J Oglesby; B L Hsi; E M Adams; J P Atkinson
Journal:  Clin Exp Immunol       Date:  1991-02       Impact factor: 4.330

9.  Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism.

Authors:  T J Oglesby; C J Allen; M K Liszewski; D J White; J P Atkinson
Journal:  J Exp Med       Date:  1992-06-01       Impact factor: 14.307

Review 10.  Identification of sperm immunoreactive antigens for immunocontraceptive purposes: a review.

Authors:  Alina Domagala; Maciej Kurpisz
Journal:  Reprod Biol Endocrinol       Date:  2004-03-18       Impact factor: 5.211
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.