Literature DB >> 24623658

Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo.

Yizhou Dong1, Ahmed A Eltoukhy, Christopher A Alabi, Omar F Khan, Omid Veiseh, J Robert Dorkin, Sasilada Sirirungruang, Hao Yin, Benjamin C Tang, Jeisa M Pelet, Delai Chen, Zhen Gu, Yuan Xue, Robert Langer, Daniel G Anderson.   

Abstract

New lipid-like nanomaterials are developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles are shown to induce simultaneous gene expression and silencing both in vitro and in vivo.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  gene expression; gene silencing; lipid-like nanomaterials; plasmid DNA; siRNA

Mesh：

Substances：

Year:  2014        PMID： 24623658      PMCID： PMC4160381          DOI： 10.1002/adhm.201400054

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  31 in total

Review 1.  Beyond Mendel: an evolving view of human genetic disease transmission.

Authors:  Jose L Badano; Nicholas Katsanis
Journal:  Nat Rev Genet       Date:  2002-10       Impact factor: 53.242

Review 2.  Multicomponent therapeutics for networked systems.

Authors:  Curtis T Keith; Alexis A Borisy; Brent R Stockwell
Journal:  Nat Rev Drug Discov       Date:  2005-01       Impact factor: 84.694

Review 3.  The efficiency of multi-target drugs: the network approach might help drug design.

Authors:  Péter Csermely; Vilmos Agoston; Sándor Pongor
Journal:  Trends Pharmacol Sci       Date:  2005-04       Impact factor: 14.819

4.  A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium.

Authors:  A Santel; M Aleku; O Keil; J Endruschat; V Esche; G Fisch; S Dames; K Löffler; M Fechtner; W Arnold; K Giese; A Klippel; J Kaufmann
Journal:  Gene Ther       Date:  2006-04-20       Impact factor: 5.250

Review 5.  Cancer gene therapy: fringe or cutting edge?

Authors:  F McCormick
Journal:  Nat Rev Cancer       Date:  2001-11       Impact factor: 60.716

6.  RNAi-mediated gene silencing in non-human primates.

Authors:  Tracy S Zimmermann; Amy C H Lee; Akin Akinc; Birgit Bramlage; David Bumcrot; Matthew N Fedoruk; Jens Harborth; James A Heyes; Lloyd B Jeffs; Matthias John; Adam D Judge; Kieu Lam; Kevin McClintock; Lubomir V Nechev; Lorne R Palmer; Timothy Racie; Ingo Röhl; Stephan Seiffert; Sumi Shanmugam; Vandana Sood; Jürgen Soutschek; Ivanka Toudjarska; Amanda J Wheat; Ed Yaworski; William Zedalis; Victor Koteliansky; Muthiah Manoharan; Hans-Peter Vornlocher; Ian MacLachlan
Journal:  Nature       Date:  2006-03-26       Impact factor: 49.962

Review 7.  Genetic disease since 1945.

Authors:  M S Lindee
Journal:  Nat Rev Genet       Date:  2000-12       Impact factor: 53.242

Review 8.  Molecular genetics of human prostate cancer.

Authors:  Mark A Rubin; Angelo M De Marzo
Journal:  Mod Pathol       Date:  2004-03       Impact factor: 7.842

9.  A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.

Authors:  Akin Akinc; Andreas Zumbuehl; Michael Goldberg; Elizaveta S Leshchiner; Valentina Busini; Naushad Hossain; Sergio A Bacallado; David N Nguyen; Jason Fuller; Rene Alvarez; Anna Borodovsky; Todd Borland; Rainer Constien; Antonin de Fougerolles; J Robert Dorkin; K Narayanannair Jayaprakash; Muthusamy Jayaraman; Matthias John; Victor Koteliansky; Muthiah Manoharan; Lubomir Nechev; June Qin; Timothy Racie; Denitza Raitcheva; Kallanthottathil G Rajeev; Dinah W Y Sah; Jürgen Soutschek; Ivanka Toudjarska; Hans-Peter Vornlocher; Tracy S Zimmermann; Robert Langer; Daniel G Anderson
Journal:  Nat Biotechnol       Date:  2008-04-27       Impact factor: 54.908

10.  A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

Authors:  Laura J Scott; Karen L Mohlke; Lori L Bonnycastle; Cristen J Willer; Yun Li; William L Duren; Michael R Erdos; Heather M Stringham; Peter S Chines; Anne U Jackson; Ludmila Prokunina-Olsson; Chia-Jen Ding; Amy J Swift; Narisu Narisu; Tianle Hu; Randall Pruim; Rui Xiao; Xiao-Yi Li; Karen N Conneely; Nancy L Riebow; Andrew G Sprau; Maurine Tong; Peggy P White; Kurt N Hetrick; Michael W Barnhart; Craig W Bark; Janet L Goldstein; Lee Watkins; Fang Xiang; Jouko Saramies; Thomas A Buchanan; Richard M Watanabe; Timo T Valle; Leena Kinnunen; Gonçalo R Abecasis; Elizabeth W Pugh; Kimberly F Doheny; Richard N Bergman; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke
Journal:  Science       Date:  2007-04-26       Impact factor: 47.728
View more
  19 in total

1.  Preparation and Optimization of Lipid-Like Nanoparticles for mRNA Delivery.

Authors:  Bin Li; Yizhou Dong
Journal:  Methods Mol Biol       Date:  2017

Review 2.  Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems.

Authors:  S Guan; J Rosenecker
Journal:  Gene Ther       Date:  2017-01-17       Impact factor: 5.250

Review 3.  Transfection by cationic gemini lipids and surfactants.

Authors:  M Damen; A J J Groenen; S F M van Dongen; R J M Nolte; B J Scholte; M C Feiters
Journal:  Medchemcomm       Date:  2018-07-17       Impact factor: 3.597

4.  Intracellular Delivery of His-Tagged Genome-Editing Proteins Enabled by Nitrilotriacetic Acid-Containing Lipidoid Nanoparticles.

Authors:  Yamin Li; Alice Chukun Li; Qiaobing Xu
Journal:  Adv Healthc Mater       Date:  2018-11-22       Impact factor: 9.933

Review 5.  Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy.

Authors:  Anish Babu; Ranganayaki Muralidharan; Narsireddy Amreddy; Meghna Mehta; Anupama Munshi; Rajagopal Ramesh
Journal:  IEEE Trans Nanobioscience       Date:  2016-12       Impact factor: 2.935

Review 6.  Nanoformulations for combination or cascade anticancer therapy.

Authors:  Lei Miao; Shutao Guo; C Michael Lin; Qi Liu; Leaf Huang
Journal:  Adv Drug Deliv Rev       Date:  2017-06-15       Impact factor: 15.470

7.  Biodegradable Amino-Ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo.

Authors:  Xinfu Zhang; Bin Li; Xiao Luo; Weiyu Zhao; Justin Jiang; Chengxiang Zhang; Min Gao; Xiaofang Chen; Yizhou Dong
Journal:  ACS Appl Mater Interfaces       Date:  2017-07-19       Impact factor: 9.229

Review 8.  Nanoscale platforms for messenger RNA delivery.

Authors:  Bin Li; Xinfu Zhang; Yizhou Dong
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2018-05-04

9.  An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo.

Authors:  Bin Li; Xiao Luo; Binbin Deng; Junfeng Wang; David W McComb; Yimin Shi; Karin M L Gaensler; Xu Tan; Amy L Dunn; Bryce A Kerlin; Yizhou Dong
Journal:  Nano Lett       Date:  2015-11-06       Impact factor: 11.189

Review 10.  Recent advances of cocktail chemotherapy by combination drug delivery systems.

Authors:  Quanyin Hu; Wujin Sun; Chao Wang; Zhen Gu
Journal:  Adv Drug Deliv Rev       Date:  2015-11-06       Impact factor: 15.470
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.