OBJECTIVE: To investigate the relationship of apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values with renal function on 3T diffusion tensor imaging (DTI) in chronic kidney disease. MATERIALS AND METHODS: Twenty healthy volunteers and 29 patients with CKD underwent DTI. The relationship among ADC, FA, and renal function was analyzed. RESULTS: Cortical and medullary ADC and FA values of patients with chronic kidney disease were lower than those of healthy volunteers (P = 0.000). Both the renal ADC and FA values correlated inversely with serum creatinine and blood urea nitrogen (P < 0.05). CONCLUSION: DTI is a feasible and non-invasive means to reflect the severity of renal function damaged.
OBJECTIVE: To investigate the relationship of apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values with renal function on 3T diffusion tensor imaging (DTI) in chronic kidney disease. MATERIALS AND METHODS: Twenty healthy volunteers and 29 patients with CKD underwent DTI. The relationship among ADC, FA, and renal function was analyzed. RESULTS: Cortical and medullary ADC and FA values of patients with chronic kidney disease were lower than those of healthy volunteers (P = 0.000). Both the renal ADC and FA values correlated inversely with serum creatinine and blood ureanitrogen (P < 0.05). CONCLUSION: DTI is a feasible and non-invasive means to reflect the severity of renal function damaged.
Authors: Hao Song; Dan Ruan; Wenyang Liu; V Andrew Stenger; Rolf Pohmann; Maria A Fernández-Seara; Tejas Nair; Sungkyu Jung; Jingqin Luo; Yuichi Motai; Jingfei Ma; John D Hazle; H Michael Gach Journal: Med Phys Date: 2017-02-21 Impact factor: 4.071
Authors: Anna Caroli; Moritz Schneider; Iris Friedli; Alexandra Ljimani; Sophie De Seigneux; Peter Boor; Latha Gullapudi; Isma Kazmi; Iosif A Mendichovszky; Mike Notohamiprodjo; Nicholas M Selby; Harriet C Thoeny; Nicolas Grenier; Jean-Paul Vallée Journal: Nephrol Dial Transplant Date: 2018-09-01 Impact factor: 5.992