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Literature DB >> 24621955

Induction of pluripotency by defined factors.

Koji Tanabe¹, Kazutoshi Takahashi, Shinya Yamanaka.

Abstract

The "reversion of cell fate from differentiated states back into totipotent or pluripotent states" has been an interest of many scientists for a long time. With the help of knowledge accumulated by those scientists, we succeeded in converting somatic cells to a pluripotent cell lineage by the forced expression of defined factors. These established induced pluripotent stem (iPS) cells have similar features to embryonic stem (ES) cells, including pluripotency and immortality. The iPS cell technology provides unprecedented opportunities for regenerative medicine and drug discovery.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2014 PMID： 24621955 PMCID： PMC3997808 DOI： 10.2183/pjab.90.83

Source DB: PubMed Journal: Proc Jpn Acad Ser B Phys Biol Sci ISSN： 0386-2208 Impact factor: 3.493

104 in total

1. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.

Authors: Nimet Maherali; Rupa Sridharan; Wei Xie; Jochen Utikal; Sarah Eminli; Katrin Arnold; Matthias Stadtfeld; Robin Yachechko; Jason Tchieu; Rudolf Jaenisch; Kathrin Plath; Konrad Hochedlinger
Journal: Cell Stem Cell Date: 2007-06-07 Impact factor: 24.633

2. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.

Authors: M Tada; T Tada; L Lefebvre; S C Barton; M A Surani
Journal: EMBO J Date: 1997-11-03 Impact factor: 11.598

3. Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.

Authors: Satoshi Nori; Yohei Okada; Akimasa Yasuda; Osahiko Tsuji; Yuichiro Takahashi; Yoshiomi Kobayashi; Kanehiro Fujiyoshi; Masato Koike; Yasuo Uchiyama; Eiji Ikeda; Yoshiaki Toyama; Shinya Yamanaka; Masaya Nakamura; Hideyuki Okano
Journal: Proc Natl Acad Sci U S A Date: 2011-09-26 Impact factor: 11.205

4. Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.

Authors: Kazutoshi Takahashi; Kaoru Mitsui; Shinya Yamanaka
Journal: Nature Date: 2003-05-29 Impact factor: 49.962

5. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Authors: César Cobaleda; Wolfram Jochum; Meinrad Busslinger
Journal: Nature Date: 2007-09-12 Impact factor: 49.962

6. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors: Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal: Nature Date: 2007-06-06 Impact factor: 49.962

7. iPS cells produce viable mice through tetraploid complementation.

Authors: Xiao-yang Zhao; Wei Li; Zhuo Lv; Lei Liu; Man Tong; Tang Hai; Jie Hao; Chang-long Guo; Qing-wen Ma; Liu Wang; Fanyi Zeng; Qi Zhou
Journal: Nature Date: 2009-09-03 Impact factor: 49.962

8. Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells.

Authors: Ryoko Araki; Masahiro Uda; Yuko Hoki; Misato Sunayama; Miki Nakamura; Shunsuke Ando; Mayumi Sugiura; Hisashi Ideno; Akemi Shimada; Akira Nifuji; Masumi Abe
Journal: Nature Date: 2013-01-09 Impact factor: 49.962

9. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors: Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal: Nat Biotechnol Date: 2007-11-30 Impact factor: 54.908

10. Direct cell reprogramming is a stochastic process amenable to acceleration.

Authors: Jacob Hanna; Krishanu Saha; Bernardo Pando; Jeroen van Zon; Christopher J Lengner; Menno P Creyghton; Alexander van Oudenaarden; Rudolf Jaenisch
Journal: Nature Date: 2009-11-08 Impact factor: 49.962

13 in total

Review 1. Role of Hox genes in stem cell differentiation.

Authors: Anne Seifert; David F Werheid; Silvana M Knapp; Edda Tobiasch
Journal: World J Stem Cells Date: 2015-04-26 Impact factor: 5.326

2. Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming.

Authors: Joshua Chan; Patrick Y Kim; Emiko Kranz; Yoshiko Nagaoka; YooJin Lee; Jing Wen; Heidi J Elsaesser; Meng Qin; David G Brooks; Gene-Errol Ringpis; Irvin S Y Chen; Masakazu Kamata
Journal: AIDS Res Hum Retroviruses Date: 2017-11 Impact factor: 2.205

Review 3. Aging and longevity in the simplest animals and the quest for immortality.

Authors: Ronald S Petralia; Mark P Mattson; Pamela J Yao
Journal: Ageing Res Rev Date: 2014-06-05 Impact factor: 10.895

4. Binary colloidal crystals (BCCs) as a feeder-free system to generate human induced pluripotent stem cells (hiPSCs).

Authors: Peng-Yuan Wang; Sandy Shen-Chi Hung; Helmut Thissen; Peter Kingshott; Raymond Ching-Bong Wong
Journal: Sci Rep Date: 2016-11-11 Impact factor: 4.379

5. Characteristic analyses of a neural differentiation model from iPSC-derived neuron according to morphology, physiology, and global gene expression pattern.

Authors: Sai Kang; Xiaoxia Chen; Siyi Gong; Panpan Yu; SukYu Yau; Zhenghui Su; Libing Zhou; Jiandong Yu; Guangjin Pan; Lingling Shi
Journal: Sci Rep Date: 2017-09-25 Impact factor: 4.379

Review 6. Evidence-Based Theory for Integrated Genome Regulation of Ontogeny--An Unprecedented Role of Nuclear FGFR1 Signaling.

Authors: Michal K Stachowiak; Ewa K Stachowiak
Journal: J Cell Physiol Date: 2016-02-02 Impact factor: 6.384