| Literature DB >> 24613991 |
Olena S Tokareva1, Shangchao Lin2, Matthew M Jacobsen3, Wenwen Huang4, Daniel Rizzo5, David Li3, Marc Simon5, Cristian Staii5, Peggy Cebe5, Joyce Y Wong3, Markus J Buehler2, David L Kaplan6.
Abstract
Bioengineered spider silk block copolymers were studied to understand the effect of protein chain length and sequence chemistry on the formation of secondary structure and materials assembly. Using a combination of in vitro protein design and assembly studies, we demonstrate that silk block copolymers possessing multiple repetitive units self-assemble into lamellar microstructures. Additionally, the study provides insights into the assembly behavior of spider silk block copolymers in concentrated salt solutions.Entities:
Keywords: Block copolymers; Modeling; Self-assembly; Silk
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Year: 2014 PMID： 24613991 PMCID： PMC4040161 DOI： 10.1016/j.jsb.2014.03.004
Source DB: PubMed Journal: J Struct Biol ISSN： 1047-8477 Impact factor: 2.867