| Literature DB >> 24613261 |
Anna Jesionowska1, Elzbieta Cecerska2, Barbara Dolegowska2.
Abstract
Lysophosphatidic acid (LPA) is a bioactive lipid involved in cellular signal transduction. LPA plays a role in both physiological and pathological processes. Elevated levels of LPA are observed in the plasma of patients with epithelial ovarian cancer, indicating its potential as a diagnostic marker. Quantification of total LPA can be performed by radioenzymatic, fluorometric, colorimetric, or immunoezymatic assay. Determination of individual LPA molecular species requires the use of capillary electrophoresis, gas chromatography, thin layer chromatography, liquid chromatography, or a matrix-assisted laser desorption/ionization time-of-flight method connected to an appropriate detection system.Entities:
Keywords: Lysophosphatidic acid; Methods; Quantifying
Mesh:
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Year: 2014 PMID: 24613261 DOI: 10.1016/j.ab.2014.02.021
Source DB: PubMed Journal: Anal Biochem ISSN: 0003-2697 Impact factor: 3.365