Literature DB >> 2461195

Characterization of receptor for granulocyte colony-stimulating factor on human circulating neutrophils.

H Uzumaki1, T Okabe, N Sasaki, K Hagiwara, F Takaku, S Itoh.   

Abstract

We have made a mutein of human G-CSF with more stable, and potent biological activity. Using 125 I-labeled mutein human G-CSF, high affinity binding sites were identified on human circulating neutrophils. Receptor number per cell was 560 with a Kd of 250 pM. The human G-CSF receptor was identified as a single subunit protein of Mr approximately 150,000.

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Year:  1988        PMID： 2461195     DOI： 10.1016/s0006-291x(88)80947-1

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Effect of recombinant human granulocyte colony-stimulating factor on human neutrophil adherence in vitro.

Authors:  Y Okada; M Kawagishi; M Kusaka
Journal:  Experientia       Date:  1990-10-15

2.  Hematopoietic growth factor receptors.

Authors:  J H Shieh; M A Moore
Journal:  Cytotechnology       Date:  1989-12       Impact factor: 2.058

3.  Identification of a functional receptor for granulocyte colony-stimulating factor on platelets.

Authors:  K Shimoda; S Okamura; N Harada; S Kondo; T Okamura; Y Niho
Journal:  J Clin Invest       Date:  1993-04       Impact factor: 14.808

4.  Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation.

Authors:  F Dong; C van Buitenen; K Pouwels; L H Hoefsloot; B Löwenberg; I P Touw
Journal:  Mol Cell Biol       Date:  1993-12       Impact factor: 4.272

5.  Identification and characterization of receptors for granulocyte colony-stimulating factor on human placenta and trophoblastic cells.

Authors:  H Uzumaki; T Okabe; N Sasaki; K Hagiwara; F Takaku; M Tobita; K Yasukawa; S Ito; Y Umezawa
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

6.  Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.

Authors:  A Larsen; T Davis; B M Curtis; S Gimpel; J E Sims; D Cosman; L Park; E Sorensen; C J March; C A Smith
Journal:  J Exp Med       Date:  1990-12-01       Impact factor: 14.307
  6 in total

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