Literature DB >> 1699783

Effect of recombinant human granulocyte colony-stimulating factor on human neutrophil adherence in vitro.

Y Okada1, M Kawagishi, M Kusaka.   

Abstract

We measured the effects of recombinant human granulocyte-colony stimulating factor (rhG-CSF) on the adherence of human neutrophils by using a dacron fiber system to assay the adhesive ability of neutrophils. rhG-CSF enhanced neutrophil adherence to dacron fibers. N-formyl-methionyl-leucyl-phenylalanine (fMLP) induced neutrophil-neutrophil interaction (neutrophil aggregation) in addition to neutrophil-dacron interaction, whereas rhG-CSF did not cause neutrophil aggregation. These results indicated that rhG-CSF increases the adhesive ability of neutrophils without neutrophil-neutrophil interaction, and the action of rhG-CSF in neutrophil activation is different from the neutrophil activation caused by fMLP.

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Year:  1990        PMID： 1699783     DOI： 10.1007/bf01940670

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  22 in total

1.  Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries.

Authors:  G S Worthen; B Schwab; E L Elson; G P Downey
Journal:  Science       Date:  1989-07-14       Impact factor: 47.728

2.  The effect of intravascular neutrophil chemotactic factors on blood neutrophil and platelet kinetics.

Authors:  A C Issekutz; M Ripley
Journal:  Am J Hematol       Date:  1986-02       Impact factor: 10.047

3.  Effects of adrenergic alpha- and beta-receptor stimulation on the release of lymphocytes and granulocytes from the spleen.

Authors:  U Ernström; G Sandberg
Journal:  Scand J Haematol       Date:  1973

4.  Effects of recombinant human granulocyte and macrophage colony-stimulating factors on signal transduction pathways in human granulocytes.

Authors:  R Sullivan; J D Griffin; E R Simons; A I Schafer; T Meshulam; J P Fredette; A K Maas; A S Gadenne; J L Leavitt; D A Melnick
Journal:  J Immunol       Date:  1987-11-15       Impact factor: 5.422

5.  Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide.

Authors:  S Kitagawa; A Yuo; L M Souza; M Saito; Y Miura; F Takaku
Journal:  Biochem Biophys Res Commun       Date:  1987-05-14       Impact factor: 3.575

6.  The cell surface glycoprotein Mac-1 (CD11b/CD18) mediates neutrophil adhesion and modulates degranulation independently of its quantitative cell surface expression.

Authors:  B Schleiffenbaum; R Moser; M Patarroyo; J Fehr
Journal:  J Immunol       Date:  1989-05-15       Impact factor: 5.422

7.  Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium.

Authors:  N B Vedder; J M Harlan
Journal:  J Clin Invest       Date:  1988-03       Impact factor: 14.808

8.  Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hemopoietic cells.

Authors:  D Metcalf; N A Nicola
Journal:  J Cell Physiol       Date:  1983-08       Impact factor: 6.384

9.  Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer.

Authors:  M H Bronchud; J H Scarffe; N Thatcher; D Crowther; L M Souza; N K Alton; N G Testa; T M Dexter
Journal:  Br J Cancer       Date:  1987-12       Impact factor: 7.640

10.  In vitro and in vivo analysis of the effects of recombinant human granulocyte colony-stimulating factor in patients.

Authors:  M H Bronchud; M R Potter; G Morgenstern; M J Blasco; J H Scarffe; N Thatcher; D Crowther; L M Souza; N K Alton; N G Testa
Journal:  Br J Cancer       Date:  1988-07       Impact factor: 7.640
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  1 in total

1.  Granulocyte colony-stimulating factor does not enhance phagocytosis or microbicidal activity of human mature polymorphonuclear neutrophils in vitro.

Authors:  N Shimono; K Okada; D Takeda; K Eguchi; H Misumi; Y Sawae; Y Niho
Journal:  Clin Diagn Lab Immunol       Date:  1994-09
  1 in total

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