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Literature DB >> 2460745

Identification of a second interferon-regulated murine Mx gene.

Abstract

The murine influenza virus resistance locus Mx consists of more than one interferon-responsive transcription unit. We isolated clones of the transcripts of a second Mx gene (Mx2) which is closely linked to the well-characterized resistance gene and determined their sequences. Mx2 mRNA is more than 90% identical to Mx1 mRNA in the region corresponding to the amino termini of the encoded proteins. Mx2 mRNAs of mouse strains BALB/c and CBA have open reading frames apparently interrupted by mutations. Interferon-treated cells from strain A2G and other influenza virus-resistant strains failed to express detectable amounts of Mx2 transcripts.

Entities: Gene Mutation Species

Mesh：

Substances：

Year: 1988 PMID： 2460745 PMCID： PMC365528 DOI： 10.1128/mcb.8.10.4524-4528.1988

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

15 in total

1. Mx protein: constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus.

Authors: P Staeheli; O Haller; W Boll; J Lindenmann; C Weissmann
Journal: Cell Date: 1986-01-17 Impact factor: 41.582

2. Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16.

Authors: P Staeheli; D Pravtcheva; L G Lundin; M Acklin; F Ruddle; J Lindenmann; O Haller
Journal: J Virol Date: 1986-06 Impact factor: 5.103

Review 3. Interferon-induced Mx protein: a mediator of cellular resistance to influenza virus.

Authors: P Staeheli; O Haller
Journal: Interferon Date: 1987

4. A new method for sequencing DNA.

Authors: A M Maxam; W Gilbert
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

5. Gene expression in rat brain.

Authors: R J Milner; J G Sutcliffe
Journal: Nucleic Acids Res Date: 1983-08-25 Impact factor: 16.971

Review 6. Inborn resistance of ice to orthomyxoviruses.

Authors: O Haller
Journal: Curr Top Microbiol Immunol Date: 1981 Impact factor: 4.291

7. Determination of nucleotide sequences in DNA.

Authors: F Sanger
Journal: Science Date: 1981-12-11 Impact factor: 47.728

8. Transcriptional activation of the mouse Mx gene by type I interferon.

Authors: P Staeheli; P Danielson; O Haller; J G Sutcliffe
Journal: Mol Cell Biol Date: 1986-12 Impact factor: 4.272

9. Mx-dependent resistance to influenza viruses is induced by mouse interferons alpha and beta but not gamma.

Authors: P Staeheli; M A Horisberger; O Haller
Journal: Virology Date: 1984-01-30 Impact factor: 3.616

10. Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter.

Authors: H Hug; M Costas; P Staeheli; M Aebi; C Weissmann
Journal: Mol Cell Biol Date: 1988-08 Impact factor: 4.272

37 in total

1. Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice.

Authors: Dominic Wichmann; Hermann-Josef Gröne; Michael Frese; Jovan Pavlovic; Bärbel Anheier; Otto Haller; Hans-Dieter Klenk; Heinz Feldmann
Journal: J Virol Date: 2002-09 Impact factor: 5.103

2. Molecular cloning of the pufferfish (Takifugu rubripes) Mx gene and functional characterization of its promoter.

Authors: Wai Ho Yap; Alice Tay; Sydney Brenner; Byrappa Venkatesh
Journal: Immunogenetics Date: 2003-01-09 Impact factor: 2.846

Review 3. Mouse chromosome 16.

Authors: R H Reeves; R D Miller
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

Review 4. Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity.

Authors: Otto Haller; Song Gao; Alexander von der Malsburg; Oliver Daumke; Georg Kochs
Journal: J Biol Chem Date: 2010-06-10 Impact factor: 5.157

Review 5. Mouse chromosome 16.

Authors: R H Reeves; R D Miller; R Riblet
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

Review 6. Disease resistance in farm animals.

Authors: M Müller; G Brem
Journal: Experientia Date: 1991-09-15

Review 7. Mx proteins: antiviral gatekeepers that restrain the uninvited.

Authors: Judith Verhelst; Paco Hulpiau; Xavier Saelens
Journal: Microbiol Mol Biol Rev Date: 2013-12 Impact factor: 11.056

8. Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation.

Authors: P Staeheli; R Grob; E Meier; J G Sutcliffe; O Haller
Journal: Mol Cell Biol Date: 1988-10 Impact factor: 4.272

9. MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groups.

Authors: Y Li; H Youssoufian
Journal: J Clin Invest Date: 1997-12-01 Impact factor: 14.808

10. Antiviral activity of limitin against encephalomyocarditis virus, herpes simplex virus, and mouse hepatitis virus: diverse requirements by limitin and alpha interferon for interferon regulatory factor 1.

Authors: Shin-Ichiro Kawamoto; Kenji Oritani; Hideo Asada; Isao Takahashi; Jun Ishikawa; Hitoshi Yoshida; Masahide Yamada; Naoko Ishida; Hidetoshi Ujiie; Hiroaki Masaie; Yoshiaki Tomiyama; Yuji Matsuzawa
Journal: J Virol Date: 2003-09 Impact factor: 5.103