BACKGROUND: Rate of misdiagnosis of disorders of consciousness (DoC) can be reduced by employing validated clinical diagnostic tools, such as the Coma Recovery Scale-Revised (CRS-R). An Italian version of the CRS-R has been recently developed, but its applicability across different clinical settings, and its concurrent validity and diagnostic sensitivity have not been estimated yet. AIM: To perform a multicentre validation study of the Italian version of the Coma Recovery Scale-Revised (CRS-R). DESIGN: Analysis of inter-rater reliability, concurrent validity and diagnostic sensitivity of the scale. SETTING: One Intensive Care Unit, 8 Post-acute rehabilitation centres and 2 Long-term facilities POPULATION: Twenty-seven professionals (physicians, N.=11; psychologists, N.=5; physiotherapists, N.=3; speech therapists, N.=6; nurses, N.=2) from 11 Italian Centres. METHODS: CRS-R and Disability Rating Scale (DRS) applied to 122 patients with clinical diagnosis of Vegetative State (VS) or Minimally Conscious State (MCS). RESULTS: CRS-R has good-to-excellent inter-rater reliability for all subscales, particularly for the communication subscale. The Italian version of the CRS-R showed a high sensitivity and specificity in detecting MCS with reference to clinical consensus diagnosis. The CRS-R showed good concurrent validity with the Disability Rating Scale, which had very low specificity with reference to clinical consensus diagnosis. CONCLUSIONS: The Italian version of the CRS-R is a valid scale for use from the sub-acute to chronic stages of DoC. It can be administered reliably by all members of the rehabilitation team with different specialties, levels of experience and settings. CLINICAL REHABILITATION IMPACT: The present study promote use of the Italian version of the CRS-R to improve diagnosis of DoC patients, and plan tailored rehabilitation treatment.
BACKGROUND: Rate of misdiagnosis of disorders of consciousness (DoC) can be reduced by employing validated clinical diagnostic tools, such as the Coma Recovery Scale-Revised (CRS-R). An Italian version of the CRS-R has been recently developed, but its applicability across different clinical settings, and its concurrent validity and diagnostic sensitivity have not been estimated yet. AIM: To perform a multicentre validation study of the Italian version of the Coma Recovery Scale-Revised (CRS-R). DESIGN: Analysis of inter-rater reliability, concurrent validity and diagnostic sensitivity of the scale. SETTING: One Intensive Care Unit, 8 Post-acute rehabilitation centres and 2 Long-term facilities POPULATION: Twenty-seven professionals (physicians, N.=11; psychologists, N.=5; physiotherapists, N.=3; speech therapists, N.=6; nurses, N.=2) from 11 Italian Centres. METHODS:CRS-R and Disability Rating Scale (DRS) applied to 122 patients with clinical diagnosis of Vegetative State (VS) or Minimally Conscious State (MCS). RESULTS:CRS-R has good-to-excellent inter-rater reliability for all subscales, particularly for the communication subscale. The Italian version of the CRS-R showed a high sensitivity and specificity in detecting MCS with reference to clinical consensus diagnosis. The CRS-R showed good concurrent validity with the Disability Rating Scale, which had very low specificity with reference to clinical consensus diagnosis. CONCLUSIONS: The Italian version of the CRS-R is a valid scale for use from the sub-acute to chronic stages of DoC. It can be administered reliably by all members of the rehabilitation team with different specialties, levels of experience and settings. CLINICAL REHABILITATION IMPACT: The present study promote use of the Italian version of the CRS-R to improve diagnosis of DoC patients, and plan tailored rehabilitation treatment.
Authors: Alfonso Magliacano; Francesco De Bellis; Alejandro Galvao-Carmona; Anna Estraneo; Luigi Trojano Journal: Curr Neurol Neurosci Rep Date: 2019-11-26 Impact factor: 5.081
Authors: A Pascarella; S Fiorenza; O Masotta; V Tibollo; D Vella; Anna Maria Nardone; Marta Rossi; P Volanti; F Madonia; Gaetano Cstronovo; D De Cicco; Caterina Guarnaschelli; M P Achilli; C Chiapparino; M T Angelillo; M A Tommasi; F Pisano; G Grioni; G Vezzadini; G Ferriero; S Salvaderi; R Bellazzi; Anna Estraneo Journal: Funct Neurol Date: 2018 Jan/Mar
Authors: Carlo Cavaliere; Sivayini Kandeepan; Marco Aiello; Demetrius Ribeiro de Paula; Rocco Marchitelli; Salvatore Fiorenza; Mario Orsini; Luigi Trojano; Orsola Masotta; Keith St Lawrence; Vincenzo Loreto; Blaine Alexander Chronik; Emanuele Nicolai; Andrea Soddu; Anna Estraneo Journal: Front Neurol Date: 2018-10-18 Impact factor: 4.003
Authors: Pubuditha M Abeyasinghe; Marco Aiello; Emily S Nichols; Carlo Cavaliere; Salvatore Fiorenza; Orsola Masotta; Pasquale Borrelli; Adrian M Owen; Anna Estraneo; Andrea Soddu Journal: J Clin Med Date: 2020-05-04 Impact factor: 4.241