Literature DB >> 24603359

Production of bioactive ginsenoside compound K in metabolically engineered yeast.

Xing Yan1, Yun Fan2, Wei Wei1, Pingping Wang1, Qunfang Liu3, Yongjun Wei1, Lei Zhang1, Guoping Zhao4, Jianmin Yue3, Zhihua Zhou1.   

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Year:  2014        PMID： 24603359      PMCID： PMC4042165          DOI： 10.1038/cr.2014.28

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  9 in total

Review 1.  Panax ginseng--a non-organ-specific cancer preventive?

Authors:  T K Yun
Journal:  Lancet Oncol       Date:  2001-01       Impact factor: 41.316

2.  The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers.

Authors:  Clemens Dürr; Dirk Hoffmeister; Sven-Eric Wohlert; Koji Ichinose; Monika Weber; Ursula Von Mulert; Jon S Thorson; Andreas Bechthold
Journal:  Angew Chem Int Ed Engl       Date:  2004-05-24       Impact factor: 15.336

3.  Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides.

Authors:  Zhubo Dai; Yi Liu; Xianan Zhang; Mingyu Shi; Beibei Wang; Dong Wang; Luqi Huang; Xueli Zhang
Journal:  Metab Eng       Date:  2013-10-11       Impact factor: 9.783

4.  The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng.

Authors:  Jung-Yeon Han; Hyun-Jung Kim; Yong-Soo Kwon; Yong-Eui Choi
Journal:  Plant Cell Physiol       Date:  2011-10-29       Impact factor: 4.927

5.  Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng.

Authors:  Pimpimon Tansakul; Masaaki Shibuya; Tetsuo Kushiro; Yutaka Ebizuka
Journal:  FEBS Lett       Date:  2006-09-01       Impact factor: 4.124

6.  Biotransformation of Panax notoginseng saponins into ginsenoside compound K production by Paecilomyces bainier sp. 229.

Authors:  W Zhou; Q Yan; J-Y Li; X-C Zhang; P Zhou
Journal:  J Appl Microbiol       Date:  2007-12-20       Impact factor: 3.772

Review 7.  Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid.

Authors:  Hideo Hasegawa
Journal:  J Pharmacol Sci       Date:  2004-06       Impact factor: 3.337

8.  High-level semi-synthetic production of the potent antimalarial artemisinin.

Authors:  C J Paddon; P J Westfall; D J Pitera; K Benjamin; K Fisher; D McPhee; M D Leavell; A Tai; A Main; D Eng; D R Polichuk; K H Teoh; D W Reed; T Treynor; J Lenihan; M Fleck; S Bajad; G Dang; D Dengrove; D Diola; G Dorin; K W Ellens; S Fickes; J Galazzo; S P Gaucher; T Geistlinger; R Henry; M Hepp; T Horning; T Iqbal; H Jiang; L Kizer; B Lieu; D Melis; N Moss; R Regentin; S Secrest; H Tsuruta; R Vazquez; L F Westblade; L Xu; M Yu; Y Zhang; L Zhao; J Lievense; P S Covello; J D Keasling; K K Reiling; N S Renninger; J D Newman
Journal:  Nature       Date:  2013-04-10       Impact factor: 49.962

9.  Transcriptome analysis reveals ginsenosides biosynthetic genes, microRNAs and simple sequence repeats in Panax ginseng C. A. Meyer.

Authors:  Chunfang Li; Yingjie Zhu; Xu Guo; Chao Sun; Hongmei Luo; Jingyuan Song; Ying Li; Lizhi Wang; Jun Qian; Shilin Chen
Journal:  BMC Genomics       Date:  2013-04-11       Impact factor: 3.969
  9 in total
  58 in total

1.  Pathway mining-based integration of critical enzyme parts for de novo biosynthesis of steviolglycosides sweetener in Escherichia coli.

Authors:  Jianfeng Wang; Shiyuan Li; Zhiqiang Xiong; Yong Wang
Journal:  Cell Res       Date:  2015-09-11       Impact factor: 25.617

2.  Functional analysis of β-amyrin synthase gene in ginsenoside biosynthesis by RNA interference.

Authors:  Che Zhao; Tianhui Xu; Yanlong Liang; Shoujing Zhao; Luquan Ren; Qian Wang; Bo Dou
Journal:  Plant Cell Rep       Date:  2015-04-22       Impact factor: 4.570

Review 3.  Engineered biosynthesis of natural products in heterologous hosts.

Authors:  Yunzi Luo; Bing-Zhi Li; Duo Liu; Lu Zhang; Yan Chen; Bin Jia; Bo-Xuan Zeng; Huimin Zhao; Ying-Jin Yuan
Journal:  Chem Soc Rev       Date:  2015-05-11       Impact factor: 54.564

4.  Optimized biosynthesis of santalenes and santalols in Saccharomyces cerevisiae.

Authors:  Yuchen Wang; Xiaowei Gong; Fan Li; Shasha Zuo; Minggang Li; Jiangyuan Zhao; Xiulin Han; Mengliang Wen
Journal:  Appl Microbiol Biotechnol       Date:  2021-11-05       Impact factor: 4.813

5.  [Metabolomic changes of neonatal sepsis: an exploratory clinical study].

Authors:  Ping Tong; Fu-Rong Huang; Jun Xu; Zi-Qi Wu; Xing Hu; Ming Ling; Die Wang; Bu-Fei Wu; Du-Jiao Yang; Ai-Min Zhang
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2022-06-15

Review 6.  Biotechnological production of betulinic acid and derivatives and their applications.

Authors:  Tianyue An; Wenlong Zha; Jiachen Zi
Journal:  Appl Microbiol Biotechnol       Date:  2020-02-28       Impact factor: 4.813

7.  Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides.

Authors:  Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang
Journal:  Planta       Date:  2018-09-15       Impact factor: 4.116

8.  Heterologous production of a ginsenoside saponin (compound K) and its precursors in transgenic tobacco impairs the vegetative and reproductive growth.

Authors:  Yu Shin Gwak; Jung Yeon Han; Prakash Babu Adhikari; Chang Ho Ahn; Yong Eui Choi
Journal:  Planta       Date:  2017-02-27       Impact factor: 4.116

9.  Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major.

Authors:  Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao
Journal:  Planta       Date:  2021-04-05       Impact factor: 4.116

Review 10.  20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases.

Authors:  Laurence Dinan; Waly Dioh; Stanislas Veillet; Rene Lafont
Journal:  Biomedicines       Date:  2021-04-29
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