Casilda Olveira1, Gabriel Olveira2, Francisco Espildora3, Rosa-María Girón4, Montserrat Vendrell5, Antonio Dorado6, Miguel-Ángel Martínez-García7. 1. Pneumology, Malaga Regional University Hospital, Instituto de Biomedicina de Málaga (IBIMA), Universidad de Málaga, Spain. Electronic address: casi1547@separ.es. 2. Endocrinology and Nutrition, Malaga Regional University Hospital, Instituto de Biomedicina de Málaga (IBIMA), Universidad de Málaga, Spain; CIBERDEM, CIBER of Diabetes and Associated Metabolic Diseases (Instituto de Salud Carlos III: CB07/08/0019). Electronic address: gabrielm.olveira.sspa@juntadeandalucia.es. 3. Pneumology, Malaga Regional University Hospital, Málaga, Spain. Electronic address: espildorilla@hotmail.com. 4. Pneumology, Instituto de Investigación la Princesa Hospital, Madrid, Spain. Electronic address: rmgiron@gmail.com. 5. Pneumology, Girona Biomedical Research Institute (IDIBGI), Dr. Trueta University Hospital, CIBERes (CIBER respiratory diseases), Girona, Spain. Electronic address: mvendrell.girona.ics@gencat.cat. 6. Pneumology, Malaga Regional University Hospital, Malaga, Spain. Electronic address: antoniodoradog@hotmail.com. 7. Pneumology, Polytechnic and University La Fe Hospital, CIBERes (CIBER respiratory diseases), Valencia, Spain. Electronic address: mianmartinezgarcia@gmail.com.
Abstract
BACKGROUND: The aim was to measure symptoms of depression and anxiety in patients with bronchiectasis and evaluate their relationship with a Mediterranean diet. METHODS: This cross-sectional study recruited patients with bronchiectasis at four Spanish centers. Patients completed the hospital anxiety and depression scale (HADS) and the Mediterranean diet questionnaire (PREDIMED). Demographic, health and outcome data were recorded from medical charts. Logistic regression was used to determine the predictors of elevated symptoms of depression and anxiety (HADS≥11). RESULTS: Of the 205 participants recruited, 37 (18.0%) had elevated anxiety-related scores and 26 (12.7%) had elevated depression-related scores (HADS≥11). Increased symptoms of depression were significantly associated with being unemployed, a lower education, older age, comorbidity, major dyspnea, worse quality of life (QOL) and a lower PREDIMED score. Increased symptoms of anxiety were significantly associated with more exacerbations, worse QOL and a lower PREDIMED score. Regression analyses indicated that, after adjustment, QOL and the PREDIMED score predicted elevated symptoms of depression and QOL predicted elevated symptoms of anxiety. CONCLUSIONS: The prevalence of elevated symptoms of depression and anxiety is high in patients with bronchiectasis and greater adherence to a Mediterranean diet is associated with a lower likelihood of having these symptoms, particularly for depression.
BACKGROUND: The aim was to measure symptoms of depression and anxiety in patients with bronchiectasis and evaluate their relationship with a Mediterranean diet. METHODS: This cross-sectional study recruited patients with bronchiectasis at four Spanish centers. Patients completed the hospital anxiety and depression scale (HADS) and the Mediterranean diet questionnaire (PREDIMED). Demographic, health and outcome data were recorded from medical charts. Logistic regression was used to determine the predictors of elevated symptoms of depression and anxiety (HADS≥11). RESULTS: Of the 205 participants recruited, 37 (18.0%) had elevated anxiety-related scores and 26 (12.7%) had elevated depression-related scores (HADS≥11). Increased symptoms of depression were significantly associated with being unemployed, a lower education, older age, comorbidity, major dyspnea, worse quality of life (QOL) and a lower PREDIMED score. Increased symptoms of anxiety were significantly associated with more exacerbations, worse QOL and a lower PREDIMED score. Regression analyses indicated that, after adjustment, QOL and the PREDIMED score predicted elevated symptoms of depression and QOL predicted elevated symptoms of anxiety. CONCLUSIONS: The prevalence of elevated symptoms of depression and anxiety is high in patients with bronchiectasis and greater adherence to a Mediterranean diet is associated with a lower likelihood of having these symptoms, particularly for depression.