Deborah Van Cauwenbergh1, Jo Nijs, Daphne Kos, Laura Van Weijnen, Filip Struyf, Mira Meeus. 1. Pain in Motion Research Group, Departments of Human Physiology and Rehabilitation Sciences, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Brussel, Belgium; Pain in Motion Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Abstract
INTRODUCTION: It is hypothesised that the autonomic nervous system responds differently to various stressors in patients with chronic fatigue syndrome (CFS) compared with healthy controls. The goal is to systematically review the scientific literature addressing the functioning of the autonomic nervous system in patients with CFS. MATERIALS AND METHODS: All studies that were identified through electronic databases (PubMed and Web of Science) were screened for eligibility based on the selection criteria and assessed (two independent raters) for methodological quality using a methodological checklist for case-control studies. RESULTS: Twenty-seven case-control studies were included. The methodological quality varied between 50% and 71·4%. Some studies showed different responses to head-up tilt and other autonomous testing. CONCLUSION: Although comparison between the included case-control studies was difficult, we can conclude that there are differences in autonomous response between patients with CFS and healthy controls. The heart rate dynamic response during the head-up tilt test differs between patients with CFS and healthy controls, supporting the increased prevalence of postural orthostatic tachycardia syndrome. The autonomic response can be useful for the diagnosis of CFS.
INTRODUCTION: It is hypothesised that the autonomic nervous system responds differently to various stressors in patients with chronic fatigue syndrome (CFS) compared with healthy controls. The goal is to systematically review the scientific literature addressing the functioning of the autonomic nervous system in patients with CFS. MATERIALS AND METHODS: All studies that were identified through electronic databases (PubMed and Web of Science) were screened for eligibility based on the selection criteria and assessed (two independent raters) for methodological quality using a methodological checklist for case-control studies. RESULTS: Twenty-seven case-control studies were included. The methodological quality varied between 50% and 71·4%. Some studies showed different responses to head-up tilt and other autonomous testing. CONCLUSION: Although comparison between the included case-control studies was difficult, we can conclude that there are differences in autonomous response between patients with CFS and healthy controls. The heart rate dynamic response during the head-up tilt test differs between patients with CFS and healthy controls, supporting the increased prevalence of postural orthostatic tachycardia syndrome. The autonomic response can be useful for the diagnosis of CFS.
Authors: Anna C Z Rodrigues; Maria L Messi; Zhong-Min Wang; Martin C Abba; Andrea Pereyra; Alexander Birbrair; Tan Zhang; Meaghan O'Meara; Ping Kwan; Elsa I S Lopez; Monte S Willis; Akiva Mintz; D Clark Files; Cristina Furdui; Ronald W Oppenheim; Osvaldo Delbono Journal: Acta Physiol (Oxf) Date: 2018-10-22 Impact factor: 6.311
Authors: Scott J Fatt; Jessica E Beilharz; Michael Joubert; Chloe Wilson; Andrew R Lloyd; Uté Vollmer-Conna; Erin Cvejic Journal: J Clin Sleep Med Date: 2019-11-27 Impact factor: 4.062