Literature DB >> 28168561

Health-related quality of life and suicide risk in postural tachycardia syndrome.

Cathy L Pederson1, Jill Blettner Brook2.   

Abstract

PURPOSE: Postural tachycardia syndrome (POTS) is a disorder featured by orthostatic intolerance. The purpose of this study was to investigate the severity of quality of life issues in POTS patients.
METHODS: Online surveys for health related quality of life, sleep quality, fatigue, pain, and suicidal ideation were completed by 624 POTS patients and 139 controls.
RESULTS: People with POTS have significantly more days of poor physical health (p < 0.001), fewer days with good energy (p < 0.001), and significantly more days with activity limitations (p < 0.001) than controls. Pain severity was significantly higher for those with POTS (p < 0.001) while feelings of control over life was lower than controls (p < 0.001). Sleep quality and daytime fatigue were also significantly worse for those with POTS than controls (p < 0.001). Finally, those with POTS have a significantly higher risk of suicide compared with controls (p < 0.001).
INTERPRETATION: The myriad of symptoms from which many POTS patients suffer is associated with a decreased quality of life. Nearly half of our sample with POTS was at high risk for suicide. More work needs to be done to determine the underlying issues surrounding suicide in POTS so that an appropriate treatment regimen can be developed.

Entities:  

Keywords:  Pain; Postural tachycardia syndrome (POTS); Quality of life; Sleep; Suicide

Mesh:

Year:  2017        PMID: 28168561     DOI: 10.1007/s10286-017-0399-5

Source DB:  PubMed          Journal:  Clin Auton Res        ISSN: 0959-9851            Impact factor:   4.435


  30 in total

1.  Comorbidities in pediatric patients with postural orthostatic tachycardia syndrome.

Authors:  Ajitesh Ojha; Thomas C Chelimsky; Gisela Chelimsky
Journal:  J Pediatr       Date:  2010-08-17       Impact factor: 4.406

Review 2.  The impact of physical pain on suicidal thoughts and behaviors: Meta-analyses.

Authors:  Raffaella Calati; Camelia Laglaoui Bakhiyi; Sylvaine Artero; Mark Ilgen; Philippe Courtet
Journal:  J Psychiatr Res       Date:  2015-09-11       Impact factor: 4.791

3.  Postural orthostatic tachycardia syndrome is an under-recognized condition in chronic fatigue syndrome.

Authors:  A Hoad; G Spickett; J Elliott; J Newton
Journal:  QJM       Date:  2008-09-19

Review 4.  Sleep disturbances as an evidence-based suicide risk factor.

Authors:  Rebecca A Bernert; Joanne S Kim; Naomi G Iwata; Michael L Perlis
Journal:  Curr Psychiatry Rep       Date:  2015-03       Impact factor: 5.285

5.  Visceral sensitization in postural tachycardia syndrome.

Authors:  Ramesh K Khurana
Journal:  Clin Auton Res       Date:  2014-02-09       Impact factor: 4.435

6.  A survey-based analysis of symptoms in patients with postural orthostatic tachycardia syndrome.

Authors:  Anindita Deb; Karen Morgenshtern; Collin J Culbertson; Liz B Wang; Anna DePold Hohler
Journal:  Proc (Bayl Univ Med Cent)       Date:  2015-04

Review 7.  Postural orthostatic tachycardia syndrome: a clinical review.

Authors:  Jonathan N Johnson; Kenneth J Mack; Nancy L Kuntz; Chad K Brands; Coburn J Porter; Philip R Fischer
Journal:  Pediatr Neurol       Date:  2010-02       Impact factor: 3.372

8.  Sleep disturbances and diminished quality of life in postural tachycardia syndrome.

Authors:  Kanika Bagai; Yanna Song; John F Ling; Beth Malow; Bonnie K Black; Italo Biaggioni; David Robertson; Satish R Raj
Journal:  J Clin Sleep Med       Date:  2011-04-15       Impact factor: 4.062

9.  Cognitive function, health-related quality of life, and symptoms of depression and anxiety sensitivity are impaired in patients with the postural orthostatic tachycardia syndrome (POTS).

Authors:  Jake W Anderson; Elisabeth A Lambert; Carolina I Sari; Tye Dawood; Murray D Esler; Gautam Vaddadi; Gavin W Lambert
Journal:  Front Physiol       Date:  2014-06-25       Impact factor: 4.566

10.  Sleep disturbances and autonomic dysfunction in patients with postural orthostatic tachycardia syndrome.

Authors:  Julia Mallien; Stefan Isenmann; Anne Mrazek; Carl-Albrecht Haensch
Journal:  Front Neurol       Date:  2014-07-07       Impact factor: 4.003

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  15 in total

Review 1.  Cognitive and psychological issues in postural tachycardia syndrome.

Authors:  Vidya Raj; Morwenna Opie; Amy C Arnold
Journal:  Auton Neurosci       Date:  2018-03-27       Impact factor: 3.145

2.  Is postural tachycardia syndrome in the head or in the heart? And other updates on recent autonomic research.

Authors:  Mitchell G Miglis; Srikanth Muppidi
Journal:  Clin Auton Res       Date:  2017-05-13       Impact factor: 4.435

3.  Autonomic dysfunction in sleep disorders: introduction to the series.

Authors:  Jose-Alberto Palma
Journal:  Clin Auton Res       Date:  2018-10-16       Impact factor: 4.435

4.  Postural tachycardia syndrome and suicide: what we don't know.

Authors:  Vidya Raj; Satish R Raj
Journal:  Clin Auton Res       Date:  2017-02-18       Impact factor: 4.435

Review 5.  Postural Orthostatic Tachycardia Syndrome.

Authors:  Payam Safavi-Naeini; Mehdi Razavi
Journal:  Tex Heart Inst J       Date:  2020-02-01

Review 6.  Transcranial Doppler in autonomic testing: standards and clinical applications.

Authors:  Lucy Norcliffe-Kaufmann; Brahyan Galindo-Mendez; Ana-Lucia Garcia-Guarniz; Estibaliz Villarreal-Vitorica; Vera Novak
Journal:  Clin Auton Res       Date:  2017-08-18       Impact factor: 4.435

7.  ST-segment changes during tilt-table testing in postural tachycardia syndrome: are they relevant?

Authors:  Frank I Marcus
Journal:  Clin Auton Res       Date:  2020-01-21       Impact factor: 4.435

8.  Gastrointestinal symptoms in postural tachycardia syndrome: a systematic review.

Authors:  Shahram E Mehr; Adrian Barbul; Cyndya A Shibao
Journal:  Clin Auton Res       Date:  2018-03-16       Impact factor: 4.435

Review 9.  The autonomic medical history.

Authors:  David S Goldstein; William P Cheshire
Journal:  Clin Auton Res       Date:  2017-05-27       Impact factor: 4.435

10.  Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss.

Authors:  Kate M Bourne; Derek S Chew; Lauren E Stiles; Brett H Shaw; Cyndya A Shibao; Luis E Okamoto; Emily M Garland; Alfredo Gamboa; Amanda Peltier; André Diedrich; Italo Biaggioni; Robert S Sheldon; David Robertson; Satish R Raj
Journal:  J Intern Med       Date:  2021-02-15       Impact factor: 13.068

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