Literature DB >> 24596281

Long-lasting HHV-6 reactivation in long-term adult survivors after double umbilical cord blood allogeneic stem cell transplantation.

Marina Illiaquer1, Florent Malard2, Thierry Guillaume2, Berthe-Marie Imbert-Marcille1, Jacques Delaunay2, Amandine Le Bourgeois2, Marie Rimbert3, Celine Bressollette-Bodin1, Cristina Precupanu2, Sameh Ayari2, Pierre Peterlin2, Philippe Moreau2, Mohamad Mohty4, Patrice Chevallier2.   

Abstract

Higher incidence of human herpesvirus 6 (HHV-6) infection has been documented after umbilical cord blood allo-transplant in adults. Here we demonstrate that HHV-6 reactivation persists for a very long time in half of the patients after this type of graft. Long-term immune reconstitution does not explain this event, which remains to be explained.
© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  HHV-6; PBSC; adults; allo-SCT; cord blood; immune reconstitution

Mesh：

Year:  2014        PMID： 24596281     DOI： 10.1093/infdis/jiu129

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  3 in total

1.  CD4+ T Cells Coexpressing CD134 (OX40) Harbor Significantly Increased Levels of Human Herpesvirus 6B DNA Following Umbilical Cord Blood Transplantation.

Authors:  Joshua C Pritchett; Jaime S Green; Angela M Thomm; Konstance K Knox; Michael R Verneris; Troy C Lund
Journal:  J Infect Dis       Date:  2016-10-04       Impact factor: 5.226

Review 2.  Serological evidence that activation of ubiquitous human herpesvirus-6 (HHV-6) plays a role in chronic idiopathic/spontaneous urticaria (CIU).

Authors:  D H Dreyfus
Journal:  Clin Exp Immunol       Date:  2015-11-24       Impact factor: 4.330

3.  Optimisation of a quantitative polymerase chain reaction-based strategy for the detection and quantification of human herpesvirus 6 DNA in patients undergoing allogeneic haematopoietic stem cell transplantation.

Authors:  Miriam Y H Ueda; Paulo G Alvarenga; Juliana M Real; Eloisa de Sá Moreira; Aripuanã Watanabe; Ana Maria Passos-Castilho; Matheus Vescovi; Yana Novis; Vanderson Rocha; Adriana Seber; Jose S R Oliveira; Celso A Rodrigues; Celso F H Granato
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-06-02       Impact factor: 2.743
  3 in total

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