Federica Di Berardino1, Dario Carlo Alpini2, Pietro Maria Bavera3, Piero Cecconi4, Mario Farabola4, Valentina Mattei2, Umberto Ambrosetti5, Antonio Cesarani5. 1. Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy Audiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy federica.diberardino@unimi.it. 2. ENT-Otoneurology Service, Scientific Institute S. Maria Nascente, Don C. Gnocchi Foundation, Milan, Italy. 3. Directory Board of the Italian College of Phlebology - Medick-Up Vascular Surgery and Angiology Lab, Milan, Italy. 4. Radiology and Neuroradiology Imaging Service, Fondazione Don Carlo Gnocchi, Milan, Italy. 5. Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi di Milano, Milan, Italy Audiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Abstract
OBJECTIVES: The aim of this study was to focus on patients suffering from cochleo-vestibular disorder with and without Ménière disease (MD) in order to verify whether chronic cerebrospinal drainage abnormalities could play a role in the etiopathogenesis of endolymphatic hydrops. METHODS: Fifty-two volunteers were enrolled and subdivided into two groups: 24 definite MD and 28 not-MD. Both magnetic resonance venography imaging with contrast-enhanced imaging of the venous cerebrospinal system (MRV) and venous echo-color Doppler (ECD) were performed. RESULTS: MRV showed abnormalities in 83% of MD and 57% of not-MD subjects (p < 0.001). Asymmetrical cervical venous flow, assessed by MRV, was confirmed by ECD in 62.5% of MD but in only 21.5% of not-MD subjects (p<0.001). CONCLUSION: Chronic cerebrospinal venous insufficiency might be the anatomical background, which provides a predisposing factor for the development of endolymphatic hydrops in MD patients.
OBJECTIVES: The aim of this study was to focus on patients suffering from cochleo-vestibular disorder with and without Ménière disease (MD) in order to verify whether chronic cerebrospinal drainage abnormalities could play a role in the etiopathogenesis of endolymphatic hydrops. METHODS: Fifty-two volunteers were enrolled and subdivided into two groups: 24 definite MD and 28 not-MD. Both magnetic resonance venography imaging with contrast-enhanced imaging of the venous cerebrospinal system (MRV) and venous echo-color Doppler (ECD) were performed. RESULTS: MRV showed abnormalities in 83% of MD and 57% of not-MD subjects (p < 0.001). Asymmetrical cervical venous flow, assessed by MRV, was confirmed by ECD in 62.5% of MD but in only 21.5% of not-MD subjects (p<0.001). CONCLUSION:Chronic cerebrospinal venous insufficiency might be the anatomical background, which provides a predisposing factor for the development of endolymphatic hydrops in MD patients.
Authors: Eleuterio Francisco Toro; Morena Celant; Qinghui Zhang; Christian Contarino; Nivedita Agarwal; Andreas Linninger; Lucas Omar Müller Journal: Int J Numer Method Biomed Eng Date: 2021-10-19 Impact factor: 2.648
Authors: Clive B Beggs; Christopher Magnano; Pavel Belov; Jacqueline Krawiecki; Deepa P Ramasamy; Jesper Hagemeier; Robert Zivadinov Journal: PLoS One Date: 2016-05-02 Impact factor: 3.240