Literature DB >> 24591908

The rationale behind collecting umbilical cord blood.

Nicolas H Zech1, Nikolas Broer2, Iris Ribitsch3, Mathias H Zech1, Karl-Heinz Broer3, Kubilay Ertan4, Karl-Heinz Preisegger5.   

Abstract

Umbilical cord blood (UCB) is an increasingly important and rich source of stem cells. These cells can be used for the treatment of many diseases, including cancers and immune and genetic disorders. For patients for whom no suitable related donor is available, this source of hematopoietic stem cells offers substantial advantages, notably the relative ease of procurement, the absence of risk to the donor, the small likelihood of transmitting clinically important infections, the low risk of severe graft-versus-host disease (GVHD) and the rapid availability of placental blood for transplantation centers. Even though almost 80 diseases are treatable with cord blood stem cells, 97 percent of cord blood is still disposed of after birth and lost for patients in need! To improve availability of stem cells to a broader community, efforts should be undertaken to collect cord blood and expectant parents should be properly informed of their options with regard to cord blood banking.

Entities:  

Keywords:  Stem cell; allogeneic; autologous; collection; transplantation; umbilical cord blood

Year:  2010        PMID: 24591908      PMCID: PMC3939099          DOI: 10.5152/jtgga.2010.08

Source DB:  PubMed          Journal:  J Turk Ger Gynecol Assoc        ISSN: 1309-0380


  29 in total

1.  Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients.

Authors:  J Kurtzberg; M Laughlin; M L Graham; C Smith; J F Olson; E C Halperin; G Ciocci; C Carrier; C E Stevens; P Rubinstein
Journal:  N Engl J Med       Date:  1996-07-18       Impact factor: 91.245

2.  First report of autologous cord blood transplantation in the treatment of a child with leukemia.

Authors:  Ammar Hayani; Eberhard Lampeter; David Viswanatha; David Morgan; Sharad N Salvi
Journal:  Pediatrics       Date:  2007-01       Impact factor: 7.124

Review 3.  Umbilical cord stem cell transplantation.

Authors:  Michelle A Frey; Catherine Guess; June Allison; Joanne Kurtzberg
Journal:  Semin Oncol Nurs       Date:  2009-05       Impact factor: 2.315

4.  Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia.

Authors:  Vanderson Rocha; Myriam Labopin; Guillermo Sanz; William Arcese; Rainer Schwerdtfeger; Alberto Bosi; Niels Jacobsen; Tapani Ruutu; Marcos de Lima; Jürgen Finke; Francesco Frassoni; Eliane Gluckman
Journal:  N Engl J Med       Date:  2004-11-25       Impact factor: 91.245

5.  Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling. Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources.

Authors:  V Rocha; J E Wagner; K A Sobocinski; J P Klein; M J Zhang; M M Horowitz; E Gluckman
Journal:  N Engl J Med       Date:  2000-06-22       Impact factor: 91.245

6.  Human umbilical cord blood mononuclear cells for the treatment of acute myocardial infarction.

Authors:  Robert J Henning; Hamdi Abu-Ali; John U Balis; Michael B Morgan; Alison E Willing; Paul R Sanberg
Journal:  Cell Transplant       Date:  2004       Impact factor: 4.064

7.  Unrestricted somatic stem cells from human umbilical cord blood can be differentiated into neurons with a dopaminergic phenotype.

Authors:  Susanne Greschat; Jessica Schira; Patrick Küry; Claudia Rosenbaum; Maria Angelica de Souza Silva; Gesine Kögler; Peter Wernet; Hans Werner Müller
Journal:  Stem Cells Dev       Date:  2008-04       Impact factor: 3.272

8.  Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study.

Authors:  Mary Eapen; Pablo Rubinstein; Mei-Jie Zhang; Cladd Stevens; Joanne Kurtzberg; Andromachi Scaradavou; Fausto R Loberiza; Richard E Champlin; John P Klein; Mary M Horowitz; John E Wagner
Journal:  Lancet       Date:  2007-06-09       Impact factor: 79.321

Review 9.  Unrelated donor umbilical cord blood transplantation for the treatment of hematologic malignancies.

Authors:  Craig Sauter; Juliet N Barker
Journal:  Curr Opin Hematol       Date:  2008-11       Impact factor: 3.284

10.  Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin.

Authors:  L Denner; Y Bodenburg; J G Zhao; M Howe; J Cappo; R G Tilton; J A Copland; N Forraz; C McGuckin; R Urban
Journal:  Cell Prolif       Date:  2007-06       Impact factor: 6.831

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  1 in total

1.  Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study.

Authors:  Tegenaw Tiruneh; Teklehaimanot Kiros; Sisay Getu
Journal:  BMC Pediatr       Date:  2020-09-02       Impact factor: 2.125

  1 in total

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