Literature DB >> 24589977

Pediatric low-grade gliomas: how modern biology reshapes the clinical field.

Guillaume Bergthold1, Pratiti Bandopadhayay2, Wenya Linda Bi1, Lori Ramkissoon3, Charles Stiles1, Rosalind A Segal4, Rameen Beroukhim1, Keith L Ligon3, Jacques Grill5, Mark W Kieran6.   

Abstract

Low-grade gliomas represent the most frequent brain tumors arising during childhood. They are characterized by a broad and heterogeneous group of tumors that are currently classified by the WHO according to their morphological appearance. Here we review the clinical features of these tumors, current therapeutic strategies and the recent discovery of genomic alterations characteristic to these tumors. We further explore how these recent biological findings stand to transform the treatment for these tumors and impact the diagnostic criteria for pediatric low-grade gliomas.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  BRAF; Genetics; Low-grade glioma; Pediatric

Mesh：

Year:  2014        PMID： 24589977      PMCID： PMC4082403          DOI： 10.1016/j.bbcan.2014.02.004

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  262 in total

1.  Effectiveness of novel combination chemotherapy, consisting of 5-fluorouracil, vincristine, cyclophosphamide and etoposide, in the treatment of low-grade gliomas in children.

Authors:  Mee Jeong Lee; Young Shin Ra; Jun Bum Park; Hyun Woo Goo; Seung Do Ahn; Shin Kwang Khang; Joon Sup Song; Yoon Jung Kim; Thad T Ghim
Journal:  J Neurooncol       Date:  2006-06-29       Impact factor: 4.130

2.  Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.

Authors:  Eric Bouffet; Regina Jakacki; Stewart Goldman; Darren Hargrave; Cynthia Hawkins; Manohar Shroff; Juliette Hukin; Ute Bartels; Nicholas Foreman; Stewart Kellie; Joanne Hilden; Michael Etzl; Beverly Wilson; Derek Stephens; Uri Tabori; Sylvain Baruchel
Journal:  J Clin Oncol       Date:  2012-03-05       Impact factor: 44.544

3.  A multivariate analysis of factors determining tumor progression in childhood low-grade glioma: a population-based cohort study (CCLG CNS9702).

Authors:  Tore Stokland; Jo-Fen Liu; James W Ironside; David W Ellison; Roger Taylor; Kathryn J Robinson; Susan V Picton; David A Walker
Journal:  Neuro Oncol       Date:  2010-09-22       Impact factor: 12.300

4.  Impact of chemotherapy on disseminated low-grade glioma in children and adolescents: report from the HIT-LGG 1996 trial.

Authors:  Stephan von Hornstein; Rolf-D Kortmann; Torsten Pietsch; Angela Emser; Monika Warmuth-Metz; Niels Soerensen; Ronald Straeter; Norbert Graf; Barbara Thieme; Astrid K Gnekow
Journal:  Pediatr Blood Cancer       Date:  2011-02-11       Impact factor: 3.167

5.  Gamma knife radiosurgery for low-grade astrocytomas: results of long-term follow up.

Authors:  Y Kida; T Kobayashi; Y Mori
Journal:  J Neurosurg       Date:  2000-12       Impact factor: 5.115

6.  MIB-1 labeling index in astrocytic tumors--a clinicopathologic study.

Authors:  L Neder; B O Colli; H R Machado; C G Carlotti; A C Santos; L Chimelli
Journal:  Clin Neuropathol       Date:  2004 Nov-Dec       Impact factor: 1.368

7.  BCR gene disruption in a pilomyxoid astrocytoma.

Authors:  Bárbara Meléndez; Concepción Fiaño; Yolanda Ruano; Jose L Hernández-Moneo; Manuela Mollejo; Pedro Martinez
Journal:  Neuropathology       Date:  2006-10       Impact factor: 1.906

8.  Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Authors:  David T W Jones; Barbara Hutter; Natalie Jäger; Andrey Korshunov; Marcel Kool; Hans-Jörg Warnatz; Thomas Zichner; Sally R Lambert; Marina Ryzhova; Dong Anh Khuong Quang; Adam M Fontebasso; Adrian M Stütz; Sonja Hutter; Marc Zuckermann; Dominik Sturm; Jan Gronych; Bärbel Lasitschka; Sabine Schmidt; Huriye Seker-Cin; Hendrik Witt; Marc Sultan; Meryem Ralser; Paul A Northcott; Volker Hovestadt; Sebastian Bender; Elke Pfaff; Sebastian Stark; Damien Faury; Jeremy Schwartzentruber; Jacek Majewski; Ursula D Weber; Marc Zapatka; Benjamin Raeder; Matthias Schlesner; Catherine L Worth; Cynthia C Bartholomae; Christof von Kalle; Charles D Imbusch; Sylwester Radomski; Chris Lawerenz; Peter van Sluis; Jan Koster; Richard Volckmann; Rogier Versteeg; Hans Lehrach; Camelia Monoranu; Beate Winkler; Andreas Unterberg; Christel Herold-Mende; Till Milde; Andreas E Kulozik; Martin Ebinger; Martin U Schuhmann; Yoon-Jae Cho; Scott L Pomeroy; Andreas von Deimling; Olaf Witt; Michael D Taylor; Stephan Wolf; Matthias A Karajannis; Charles G Eberhart; Wolfram Scheurlen; Martin Hasselblatt; Keith L Ligon; Mark W Kieran; Jan O Korbel; Marie-Laure Yaspo; Benedikt Brors; Jörg Felsberg; Guido Reifenberger; V Peter Collins; Nada Jabado; Roland Eils; Peter Lichter; Stefan M Pfister
Journal:  Nat Genet       Date:  2013-06-30       Impact factor: 38.330

9.  Nonrandom chromosomal gains in pilocytic astrocytomas of childhood.

Authors:  F V White; D C Anthony; E J Yunis; N J Tarbell; R M Scott; D E Schofield
Journal:  Hum Pathol       Date:  1995-09       Impact factor: 3.466

Review 10.  Pediatric low-grade gliomas and the need for new options for therapy: Why and how?

Authors:  Ibrahim Qaddoumi; Iyad Sultan; Alberto Broniscer
Journal:  Cancer Biol Ther       Date:  2009-01-22       Impact factor: 4.742
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  28 in total

Review 1.  Molecular insights into pediatric brain tumors have the potential to transform therapy.

Authors:  Amar Gajjar; Stefan M Pfister; Michael D Taylor; Richard J Gilbertson
Journal:  Clin Cancer Res       Date:  2014-11-15       Impact factor: 12.531

2.  Metastatic Low-Grade Gliomas in Children: 20 Years' Experience at St. Jude Children's Research Hospital.

Authors:  Omar Chamdine; Alberto Broniscer; Shengjie Wu; Amar Gajjar; Ibrahim Qaddoumi
Journal:  Pediatr Blood Cancer       Date:  2015-08-27       Impact factor: 3.167

3.  [Effect of bevacizumab in treatment of children with optic pathway glioma].

Authors:  Wan-Shui Wu; Jing-Jing Liu; Yan-Ling Sun; Shu-Xu DU; Chun-De Li; Miao Li; Si-Qi Ren; Jin Zhang; Xiao-Jun Gong; Li-Ming Sun
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2019-12

Review 4.  Gamma Knife treatment of low-grade gliomas in children.

Authors:  Murat Şakir Ekşi; Baran Yılmaz; Akın Akakın; Zafer Orkun Toktaş; Ahmet Cemil Kaur; Mustafa Kemal Demir; Türker Kılıç
Journal:  Childs Nerv Syst       Date:  2015-07-15       Impact factor: 1.475

Review 5.  Review of low-grade gliomas in children--evolving molecular era and therapeutic insights.

Authors:  Soumen Khatua; Jason Wang; Veena Rajaram
Journal:  Childs Nerv Syst       Date:  2015-02-27       Impact factor: 1.475

Review 6.  Chromatin remodeling defects in pediatric brain tumors.

Authors:  Alexia Klonou; Danai Spiliotakopoulou; Marios S Themistocleous; Christina Piperi; Athanasios G Papavassiliou
Journal:  Ann Transl Med       Date:  2018-06

7.  Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.

Authors:  Guillaume Bergthold; Pratiti Bandopadhayay; Yujin Hoshida; Shakti Ramkissoon; Lori Ramkissoon; Benjamin Rich; Cecile L Maire; Brenton R Paolella; Steven E Schumacher; Barbara Tabak; Ruben Ferrer-Luna; Memet Ozek; Aydin Sav; Sandro Santagata; Patrick Yung Wen; Liliana C Goumnerova; Azra H Ligon; Charles Stiles; Rosalind Segal; Todd Golub; Jacques Grill; Keith L Ligon; Jennifer A Chan; Mark W Kieran; Rameen Beroukhim
Journal:  Neuro Oncol       Date:  2015-03-29       Impact factor: 12.300

Review 8.  Molecularly Targeted Agents in the Therapy of Pediatric Brain Tumors.

Authors:  Miriam Bornhorst; Eugene I Hwang
Journal:  Paediatr Drugs       Date:  2020-02       Impact factor: 3.022

9.  Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.

Authors:  Alvaro Lassaletta; Michal Zapotocky; Matthew Mistry; Vijay Ramaswamy; Marion Honnorat; Rahul Krishnatry; Ana Guerreiro Stucklin; Nataliya Zhukova; Anthony Arnoldo; Scott Ryall; Catriona Ling; Tara McKeown; Jim Loukides; Ofelia Cruz; Carmen de Torres; Cheng-Ying Ho; Roger J Packer; Ruth Tatevossian; Ibrahim Qaddoumi; Julie H Harreld; James D Dalton; Jean Mulcahy-Levy; Nicholas Foreman; Matthias A Karajannis; Shiyang Wang; Matija Snuderl; Amulya Nageswara Rao; Caterina Giannini; Mark Kieran; Keith L Ligon; Maria Luisa Garre; Paolo Nozza; Samantha Mascelli; Alessandro Raso; Sabine Mueller; Theodore Nicolaides; Karen Silva; Romain Perbet; Alexandre Vasiljevic; Cécile Faure Conter; Didier Frappaz; Sarah Leary; Courtney Crane; Aden Chan; Ho-Keung Ng; Zhi-Feng Shi; Ying Mao; Elizabeth Finch; David Eisenstat; Bev Wilson; Anne Sophie Carret; Peter Hauser; David Sumerauer; Lenka Krskova; Valerie Larouche; Adam Fleming; Shayna Zelcer; Nada Jabado; James T Rutka; Peter Dirks; Michael D Taylor; Shiyi Chen; Ute Bartels; Annie Huang; David W Ellison; Eric Bouffet; Cynthia Hawkins; Uri Tabori
Journal:  J Clin Oncol       Date:  2017-07-20       Impact factor: 44.544

Review 10.  An integrative molecular and genomic analysis of pediatric hemispheric low-grade gliomas: an update.

Authors:  Alvaro Lassaletta; Michal Zapotocky; Eric Bouffet; Cynthia Hawkins; Uri Tabori
Journal:  Childs Nerv Syst       Date:  2016-09-20       Impact factor: 1.475
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