Literature DB >> 25722047

Review of low-grade gliomas in children--evolving molecular era and therapeutic insights.

Soumen Khatua1, Jason Wang, Veena Rajaram.   

Abstract

Low-grade gliomas are the commonest brain tumor in children comprising heterogeneous pathological entities. Though the overall prognosis is good, unresectable, and recurrent or progressive tumors in eloquent areas of the brain remain major therapeutic challenge even with advances in chemotherapeutic strategies. With the evolving surge of molecular data, improved understanding of the biology of these tumors is now perceivable that could provide insights into novel therapies. We hope the new era will enable us to profile comprehensive histopathological/molecular classification and prognostic molecular markers in these tumors and guide us to tailor optimal targeted therapy.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25722047     DOI： 10.1007/s00381-015-2653-2

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN： 0256-7040            Impact factor:   1.475


  81 in total

1.  Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.

Authors:  Eric Bouffet; Regina Jakacki; Stewart Goldman; Darren Hargrave; Cynthia Hawkins; Manohar Shroff; Juliette Hukin; Ute Bartels; Nicholas Foreman; Stewart Kellie; Joanne Hilden; Michael Etzl; Beverly Wilson; Derek Stephens; Uri Tabori; Sylvain Baruchel
Journal:  J Clin Oncol       Date:  2012-03-05       Impact factor: 44.544

2.  A multivariate analysis of factors determining tumor progression in childhood low-grade glioma: a population-based cohort study (CCLG CNS9702).

Authors:  Tore Stokland; Jo-Fen Liu; James W Ironside; David W Ellison; Roger Taylor; Kathryn J Robinson; Susan V Picton; David A Walker
Journal:  Neuro Oncol       Date:  2010-09-22       Impact factor: 12.300

3.  BCR gene disruption in a pilomyxoid astrocytoma.

Authors:  Bárbara Meléndez; Concepción Fiaño; Yolanda Ruano; Jose L Hernández-Moneo; Manuela Mollejo; Pedro Martinez
Journal:  Neuropathology       Date:  2006-10       Impact factor: 1.906

Review 4.  The WHO classification of tumors of the nervous system.

Authors:  Paul Kleihues; David N Louis; Bernd W Scheithauer; Lucy B Rorke; Guido Reifenberger; Peter C Burger; Webster K Cavenee
Journal:  J Neuropathol Exp Neurol       Date:  2002-03       Impact factor: 3.685

Review 5.  Using neurofibromatosis-1 to better understand and treat pediatric low-grade glioma.

Authors:  David H Gutmann
Journal:  J Child Neurol       Date:  2008-10       Impact factor: 1.987

6.  Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.

Authors:  Angela J Sievert; Shih-Shan Lang; Katie L Boucher; Peter J Madsen; Erin Slaunwhite; Namrata Choudhari; Meghan Kellet; Phillip B Storm; Adam C Resnick
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-26       Impact factor: 11.205

7.  High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas.

Authors:  H Deshmukh; T H Yeh; J Yu; M K Sharma; A Perry; J R Leonard; M A Watson; D H Gutmann; R Nagarajan
Journal:  Oncogene       Date:  2008-04-14       Impact factor: 9.867

8.  Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Authors:  David T W Jones; Barbara Hutter; Natalie Jäger; Andrey Korshunov; Marcel Kool; Hans-Jörg Warnatz; Thomas Zichner; Sally R Lambert; Marina Ryzhova; Dong Anh Khuong Quang; Adam M Fontebasso; Adrian M Stütz; Sonja Hutter; Marc Zuckermann; Dominik Sturm; Jan Gronych; Bärbel Lasitschka; Sabine Schmidt; Huriye Seker-Cin; Hendrik Witt; Marc Sultan; Meryem Ralser; Paul A Northcott; Volker Hovestadt; Sebastian Bender; Elke Pfaff; Sebastian Stark; Damien Faury; Jeremy Schwartzentruber; Jacek Majewski; Ursula D Weber; Marc Zapatka; Benjamin Raeder; Matthias Schlesner; Catherine L Worth; Cynthia C Bartholomae; Christof von Kalle; Charles D Imbusch; Sylwester Radomski; Chris Lawerenz; Peter van Sluis; Jan Koster; Richard Volckmann; Rogier Versteeg; Hans Lehrach; Camelia Monoranu; Beate Winkler; Andreas Unterberg; Christel Herold-Mende; Till Milde; Andreas E Kulozik; Martin Ebinger; Martin U Schuhmann; Yoon-Jae Cho; Scott L Pomeroy; Andreas von Deimling; Olaf Witt; Michael D Taylor; Stephan Wolf; Matthias A Karajannis; Charles G Eberhart; Wolfram Scheurlen; Martin Hasselblatt; Keith L Ligon; Mark W Kieran; Jan O Korbel; Marie-Laure Yaspo; Benedikt Brors; Jörg Felsberg; Guido Reifenberger; V Peter Collins; Nada Jabado; Roland Eils; Peter Lichter; Stefan M Pfister
Journal:  Nat Genet       Date:  2013-06-30       Impact factor: 38.330

9.  Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

Authors:  Mohammad Atefi; Erika von Euw; Narsis Attar; Charles Ng; Connie Chu; Deliang Guo; Ramin Nazarian; Bartosz Chmielowski; John A Glaspy; Begonya Comin-Anduix; Paul S Mischel; Roger S Lo; Antoni Ribas
Journal:  PLoS One       Date:  2011-12-14       Impact factor: 3.240

10.  Initial testing (stage 1) of the investigational mTOR kinase inhibitor MLN0128 by the pediatric preclinical testing program.

Authors:  Min H Kang; C Patrick Reynolds; John M Maris; Richard Gorlick; E Anders Kolb; Richard Lock; Hernan Carol; Stephen T Keir; Jianrong Wu; Dmitry Lyalin; Raushan T Kurmasheva; Peter J Houghton; Malcolm A Smith
Journal:  Pediatr Blood Cancer       Date:  2014-02-20       Impact factor: 3.838
View more
  3 in total

Review 1.  Conventional chemotherapy and perspectives for molecular-based oncological treatment in pediatric hemispheric low-grade gliomas.

Authors:  María Baro Fernández; Vanesa Pérez Alonso
Journal:  Childs Nerv Syst       Date:  2016-09-20       Impact factor: 1.475

2.  Pathology-MRI Correlations in Diffuse Low-Grade Epilepsy Associated Tumors.

Authors:  Aliya Al-Hajri; Salim Al-Mughairi; Alyma Somani; Shu An; Joan Liu; Anna Miserocchi; Andrew W McEvoy; Tarek Yousry; Chandrashekar Hoskote; Maria Thom
Journal:  J Neuropathol Exp Neurol       Date:  2017-12-01       Impact factor: 3.685

Review 3.  Pediatric Glioma at the Optic Pathway and Thalamus.

Authors:  Eun Suk Park; Jun Bum Park; Young-Shin Ra
Journal:  J Korean Neurosurg Soc       Date:  2018-05-01
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.