Literature DB >> 24589831

Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry.

Erik L Regalado1, Marisa C Kozlowski, John M Curto, Tobias Ritter, Michael G Campbell, Anthony R Mazzotti, Bruce C Hamper, Christopher D Spilling, Michael P Mannino, Li Wan, Jin-Quan Yu, Jinchu Liu, Christopher J Welch.   

Abstract

The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.

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Year:  2014        PMID: 24589831     DOI: 10.1039/c3ob42195c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  5 in total

1.  Palladium-catalysed electrophilic aromatic C-H fluorination.

Authors:  Kumiko Yamamoto; Jiakun Li; Jeffrey A O Garber; Julian D Rolfes; Gregory B Boursalian; Jannik C Borghs; Christophe Genicot; Jérôme Jacq; Maurice van Gastel; Frank Neese; Tobias Ritter
Journal:  Nature       Date:  2018-02-21       Impact factor: 49.962

2.  Academia-industry symbiosis in organic chemistry.

Authors:  Quentin Michaudel; Yoshihiro Ishihara; Phil S Baran
Journal:  Acc Chem Res       Date:  2015-02-23       Impact factor: 22.384

3.  Chemoselective activation of sp(3) vs sp(2) C-H bonds with Pd(II).

Authors:  John M Curto; Marisa C Kozlowski
Journal:  J Am Chem Soc       Date:  2014-12-29       Impact factor: 15.419

Review 4.  Undirected, Homogeneous C-H Bond Functionalization: Challenges and Opportunities.

Authors:  John F Hartwig; Matthew A Larsen
Journal:  ACS Cent Sci       Date:  2016-05-02       Impact factor: 14.553

5.  Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor.

Authors:  Keith W Bentley; Daysi Proano; Christian Wolf
Journal:  Nat Commun       Date:  2016-08-23       Impact factor: 14.919

  5 in total

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