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Literature DB >> 24589653

68Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers.

Brandon Nichols¹, Zhengtao Qin², Jun Yang¹, David R Vera², Neal K Devaraj¹.

Abstract

We have developed a (68)Ga metal chelating bioorthogonal tetrazine dextran probe that is highly reactive with trans-cyclooctene modified monoclonal antibodies for multistep imaging applications. Confocal microscopy and positron emission tomography (PET) were used to characterize the dextran probe in vitro and in vivo.

Entities: CellLine Chemical Disease Gene Species

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Year: 2014 PMID： 24589653 PMCID： PMC4119763 DOI： 10.1039/c3cc49530b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

23 in total

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Authors: Ji Young Choi; Byung Chul Lee
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2. (99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging.

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3. Metal-containing and related polymers for biomedical applications.

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Review 5. Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging.

Authors: Rocío García-Vázquez; Umberto Maria Battisti; Matthias M Herth
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6. Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

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Journal: Mol Imaging Biol Date: 2020-09-10 Impact factor: 3.488

8. Conformationally Strained trans-Cyclooctene (sTCO) Enables the Rapid Construction of (18)F-PET Probes via Tetrazine Ligation.

Authors: Mengzhe Wang; Dennis Svatunek; Katarina Rohlfing; Yu Liu; Hui Wang; Ben Giglio; Hong Yuan; Zhanghong Wu; Zibo Li; Joseph Fox
Journal: Theranostics Date: 2016-04-12 Impact factor: 11.556

9. Bioorthogonal tetrazine-mediated transfer reactions facilitate reaction turnover in nucleic acid-templated detection of microRNA.

Authors: Haoxing Wu; Brandon T Cisneros; Christian M Cole; Neal K Devaraj
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10. Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization.

Authors: Dennis Svatunek; Christoph Denk; Veronika Rosecker; Barbara Sohr; Christian Hametner; Günter Allmaier; Johannes Fröhlich; Hannes Mikula
Journal: Monatsh Chem Date: 2016-02-22 Impact factor: 1.451