Literature DB >> 24586106

New role for the mitochondrial peptide humanin: protective agent against chemotherapy-induced side effects.

Pinchas Cohen1.   

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Year:  2014        PMID: 24586106      PMCID: PMC3982780          DOI: 10.1093/jnci/dju006

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN: 0027-8874            Impact factor:   13.506


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  15 in total

1.  A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.

Authors:  Y Hashimoto; T Niikura; H Tajima; T Yasukawa; H Sudo; Y Ito; Y Kita; M Kawasumi; K Kouyama; M Doyu; G Sobue; T Koide; S Tsuji; J Lang; K Kurokawa; I Nishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-22       Impact factor: 11.205

Review 2.  The emerging role of the mitochondrial-derived peptide humanin in stress resistance.

Authors:  Kelvin Yen; Changhan Lee; Hemal Mehta; Pinchas Cohen
Journal:  J Mol Endocrinol       Date:  2013-01-11       Impact factor: 5.098

3.  Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment.

Authors:  Emma Eriksson; Malin Wickström; Lova Segerström Perup; John I Johnsen; Staffan Eksborg; Per Kogner; Lars Sävendahl
Journal:  J Natl Cancer Inst       Date:  2014-03-01       Impact factor: 13.506

4.  Humanin peptide suppresses apoptosis by interfering with Bax activation.

Authors:  Bin Guo; Dayong Zhai; Edelmira Cabezas; Kate Welsh; Shahrzad Nouraini; Arnold C Satterthwait; John C Reed
Journal:  Nature       Date:  2003-05-04       Impact factor: 49.962

5.  Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.

Authors:  Maaria Ikonen; Bingrong Liu; Yuichi Hashimoto; Liqun Ma; Kuk-Wha Lee; Takako Niikura; Ikuo Nishimoto; Pinchas Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-15       Impact factor: 11.205

6.  The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis.

Authors:  Y Jia; Y-H Lue; R Swerdloff; K-W Lee; L J Cobb; P Cohen; C Wang
Journal:  Andrology       Date:  2013-05-20       Impact factor: 3.842

7.  Humanin: a harbinger of mitochondrial-derived peptides?

Authors:  Changhan Lee; Kelvin Yen; Pinchas Cohen
Journal:  Trends Endocrinol Metab       Date:  2013-02-08       Impact factor: 12.015

8.  Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

Authors:  Lizzia Raffaghello; Changhan Lee; Fernando M Safdie; Min Wei; Federica Madia; Giovanna Bianchi; Valter D Longo
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-31       Impact factor: 11.205

9.  Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor.

Authors:  Guoguang Ying; Pablo Iribarren; Ye Zhou; Wanghua Gong; Ning Zhang; Zu-Xi Yu; Yingying Le; Youhong Cui; Ji Ming Wang
Journal:  J Immunol       Date:  2004-06-01       Impact factor: 5.422

10.  Humanin: a novel central regulator of peripheral insulin action.

Authors:  Radhika H Muzumdar; Derek M Huffman; Gil Atzmon; Christoph Buettner; Laura J Cobb; Sigal Fishman; Temuri Budagov; Lingguang Cui; Francine H Einstein; Aruna Poduval; David Hwang; Nir Barzilai; Pinchas Cohen
Journal:  PLoS One       Date:  2009-07-22       Impact factor: 3.240

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  15 in total

1.  The effects of humanin and its analogues on male germ cell apoptosis induced by chemotherapeutic drugs.

Authors:  Yue Jia; Aikoui Ohanyan; Yan-He Lue; Ronald S Swerdloff; Peter Y Liu; Pinchas Cohen; Christina Wang
Journal:  Apoptosis       Date:  2015-04       Impact factor: 4.677

Review 2.  Humanin: Functional Interfaces with IGF-I.

Authors:  J Xiao; S-J Kim; P Cohen; K Yen
Journal:  Growth Horm IGF Res       Date:  2016-04-07       Impact factor: 2.372

3.  The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.

Authors:  Changhan Lee; Jennifer Zeng; Brian G Drew; Tamer Sallam; Alejandro Martin-Montalvo; Junxiang Wan; Su-Jeong Kim; Hemal Mehta; Andrea L Hevener; Rafael de Cabo; Pinchas Cohen
Journal:  Cell Metab       Date:  2015-03-03       Impact factor: 27.287

4.  Humanin inhibits apoptosis in pituitary tumor cells through several signaling pathways including NF-κB activation.

Authors:  María Florencia Gottardo; Mariela Moreno Ayala; Jimena Ferraris; Sandra Zárate; Daniel Pisera; Marianela Candolfi; Gabriela Jaita; Adriana Seilicovich
Journal:  J Cell Commun Signal       Date:  2017-04-04       Impact factor: 5.782

5.  The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice.

Authors:  YanHe Lue; Ronald Swerdloff; Junxiang Wan; Jialin Xiao; Samuel French; Vince Atienza; Victor Canela; Kevin W Bruhn; Brian Stone; Yue Jia; Pinchas Cohen; Christina Wang
Journal:  Endocrinology       Date:  2015-09-18       Impact factor: 4.736

6.  Proteasome inhibition preserves longitudinal growth of denervated muscle and prevents neonatal neuromuscular contractures.

Authors:  Sia Nikolaou; Alyssa Aw Cramer; Liangjun Hu; Qingnian Goh; Douglas P Millay; Roger Cornwall
Journal:  JCI Insight       Date:  2019-12-05

Review 7.  Mitochondrial biology and prostate cancer ethnic disparity.

Authors:  Jialin Xiao; Pinchas Cohen; Mariana Carla Stern; Folakemi Odedina; John Carpten; Renee Reams
Journal:  Carcinogenesis       Date:  2018-12-13       Impact factor: 4.944

8.  The humanin analogue (HNG) prevents temozolomide-induced male germ cell apoptosis and other adverse effects in severe combined immuno-deficiency (SCID) mice bearing human medulloblastoma.

Authors:  Yue Jia; Yanhe Lue; Ronald S Swerdloff; Joseph L Lasky; Eduard H Panosyan; Jenny Dai-Ju; Christina Wang
Journal:  Exp Mol Pathol       Date:  2019-05-11       Impact factor: 4.401

9.  IGF-I regulates the age-dependent signaling peptide humanin.

Authors:  Changhan Lee; Junxiang Wan; Brian Miyazaki; Yimin Fang; Jaime Guevara-Aguirre; Kelvin Yen; Valter Longo; Andrzej Bartke; Pinchas Cohen
Journal:  Aging Cell       Date:  2014-07-18       Impact factor: 9.304

Review 10.  To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAs.

Authors:  Yuping Jia; Lichan Chen; Yukui Ma; Jian Zhang; Ningzhi Xu; Dezhong Joshua Liao
Journal:  Int J Biol Sci       Date:  2015-11-19       Impact factor: 6.580

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