Jonathan D Kort1, Caitlin Winget2, Sun H Kim3, Ruth B Lathi4. 1. Department of Obstetrics and Gynecology, Stanford University Hospital, Stanford, California. Electronic address: jkort@stanford.edu. 2. Stanford University School of Medicine, Stanford, California. 3. Division of Endocrinology, Department of Medicine, Stanford University Hospital, Stanford, California. 4. Department of Reproductive Endocrinology and Infertility, Stanford University Hospital, Stanford, California.
Abstract
OBJECTIVE: To determine if meaningful weight loss (≥10%) improved conception and live birth rates of overweight patients with infertility. DESIGN: A retrospective cohort study. SETTING: Academic medical center. PATIENT(S): Overweight patients (body mass index ≥25 kg/m(2); n = 52) being treated for infertility and referred for weight loss counseling. INTERVENTION(S): Patients were given a "meaningful" weight loss goal of 10%. They were followed by an endocrinologist who provided diet and exercise recommendations, metabolic screening, and pharmacologic intervention when indicated. MAIN OUTCOME MEASURE(S): Pregnancy rate, live birth rate, weight loss. RESULT(S): Thirty-two percent of the patients achieved meaningful weight loss. Patients achieving meaningful weight loss had significantly higher conception (88% vs. 54%) and live birth rates (71% vs. 37%) than those who did not. CONCLUSION(S): Weight loss improves live birth rates in overweight patients with infertility. Health care providers should incorporate weight loss counseling when caring for overweight patients who plan to conceive.
OBJECTIVE: To determine if meaningful weight loss (≥10%) improved conception and live birth rates of overweight patients with infertility. DESIGN: A retrospective cohort study. SETTING: Academic medical center. PATIENT(S): Overweight patients (body mass index ≥25 kg/m(2); n = 52) being treated for infertility and referred for weight loss counseling. INTERVENTION(S): Patients were given a "meaningful" weight loss goal of 10%. They were followed by an endocrinologist who provided diet and exercise recommendations, metabolic screening, and pharmacologic intervention when indicated. MAIN OUTCOME MEASURE(S): Pregnancy rate, live birth rate, weight loss. RESULT(S): Thirty-two percent of the patients achieved meaningful weight loss. Patients achieving meaningful weight loss had significantly higher conception (88% vs. 54%) and live birth rates (71% vs. 37%) than those who did not. CONCLUSION(S): Weight loss improves live birth rates in overweight patients with infertility. Health care providers should incorporate weight loss counseling when caring for overweight patients who plan to conceive.
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