Literature DB >> 24573603

Thromboprophylaxis for lung cancer patients--multimodality assessment of clinician practices, perceptions and decision support tools.

M Alexander1, S Kirsa, M MacManus, D Ball, B Solomon, K Burbury.   

Abstract

PURPOSE: The purpose of this study was to report the opinions and self-reported practices of clinicians, as well as the availability of decision support tools, regarding appropriate thromboprophylaxis for patients with lung cancer to identify variation in practice and/or divergence from evidence-based clinical practice guidelines (CPG).
METHODS: A computer-generated survey (SurveyMonkey software) was distributed to surgical, radiation and medical oncologists with lung cancer specialisation, via membership of the Australian Lung Cancer Trials Group (ALTG) from May to September 2013.
RESULTS: Seventy-two clinicians, from public, private, specialist and general hospitals, completed the survey (46% response rate). Hospital-endorsed CPG were widely available (91%); however, these routinely lacked robust recommendations for the ambulatory care setting (98%) and risk stratification tools (65%). Clinicians consistently identified ambulatory care treatment modalities (chemotherapy, alone or in combination with radiotherapy) as having similar (high) thrombotic risk as surgery. Timing and duration of pharmacological thromboprophylaxis prescribing among surgical oncologists varied and were divergent from guideline recommendations. Fifty-eight percent of surveyed clinicians cited a lack of high-quality data to guide preventative strategies in lung cancer patients.
CONCLUSION: Clinicians consistently identified patients with lung cancer as having a high thromboembolic risk in both ambulatory and surgical settings, but with differences in recommendations and variation in practice. CPG lacked robust recommendations for the ambulatory care setting, the main arena for the multimodality lung cancer treatment paradigm.

Entities:  

Mesh:

Year:  2014        PMID: 24573603     DOI: 10.1007/s00520-014-2170-y

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  37 in total

1.  Prediction of venous thromboembolism in cancer patients.

Authors:  Cihan Ay; Daniela Dunkler; Christine Marosi; Alexandru-Laurentiu Chiriac; Rainer Vormittag; Ralph Simanek; Peter Quehenberger; Christoph Zielinski; Ingrid Pabinger
Journal:  Blood       Date:  2010-09-09       Impact factor: 22.113

2.  Surgical venous thromboprophylaxis: a cross-sectional survey of canadian gynaecologic oncologists.

Authors:  Laura Hopkins; Marc Carrier; Marie Plante; Vilma Luna; Walter Gotlieb; Lisa Rambout
Journal:  J Obstet Gynaecol Can       Date:  2012-07

3.  Are patients with cancer receiving adequate thromboprophylaxis? Results from FRONTLINE.

Authors:  Robert A Wolff
Journal:  Cancer Treat Rev       Date:  2003-06       Impact factor: 12.111

4.  Thromboprophylaxis in ambulatory lung cancer treatment.

Authors:  Loretta Cavaliere
Journal:  Clin J Oncol Nurs       Date:  2013-02       Impact factor: 1.027

Review 5.  International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer.

Authors:  D Farge; P Debourdeau; M Beckers; C Baglin; R M Bauersachs; B Brenner; D Brilhante; A Falanga; G T Gerotzafias; N Haim; A K Kakkar; A A Khorana; R Lecumberri; M Mandala; M Marty; M Monreal; S A Mousa; S Noble; I Pabinger; P Prandoni; M H Prins; M H Qari; M B Streiff; K Syrigos; H Bounameaux; H R Büller
Journal:  J Thromb Haemost       Date:  2013-01       Impact factor: 5.824

6.  Thromboprophylaxis among Australasian colorectal surgeons.

Authors:  Philip Smart; Kate Burbury; Senthil Lingaratnam; A Craig Lynch; John Mackay; Alexander Heriot
Journal:  ANZ J Surg       Date:  2012-09-17       Impact factor: 1.872

7.  Incidence of venous thromboembolism among chemotherapy-treated patients with lung cancer and its association with mortality: a retrospective database study.

Authors:  Huan Huang; Jonathan R Korn; Rajiv Mallick; Mark Friedman; Christine Nichols; Joseph Menzin
Journal:  J Thromb Thrombolysis       Date:  2012-11       Impact factor: 2.300

Review 8.  Venous thromboembolism prophylaxis and treatment in cancer: a consensus statement of major guidelines panels and call to action.

Authors:  Alok A Khorana; Michael B Streiff; Dominique Farge; Mario Mandala; Philippe Debourdeau; Francis Cajfinger; Michel Marty; Anna Falanga; Gary H Lyman
Journal:  J Clin Oncol       Date:  2009-08-31       Impact factor: 44.544

9.  Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study.

Authors:  Giancarlo Agnelli; Gualberto Gussoni; Carlo Bianchini; Melina Verso; Mario Mandalà; Luigi Cavanna; Sandro Barni; Roberto Labianca; Franco Buzzi; Giovanni Scambia; Rodolfo Passalacqua; Sergio Ricci; Giampietro Gasparini; Vito Lorusso; Erminio Bonizzoni; Maurizio Tonato
Journal:  Lancet Oncol       Date:  2009-08-31       Impact factor: 41.316

10.  Thromboprophylaxis in spinal surgery: a survey.

Authors:  David J Bryson; Chika E Uzoigwe; Jason Braybrooke
Journal:  J Orthop Surg Res       Date:  2012-03-29       Impact factor: 2.359

View more
  1 in total

Review 1.  Venous thromboembolism and lung cancer: a review.

Authors:  Carolina Vitale; Maria D'Amato; Paolo Calabrò; Anna Agnese Stanziola; Mauro Mormile; Antonio Molino
Journal:  Multidiscip Respir Med       Date:  2015-09-15
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.