| Literature DB >> 2457254 |
M I Wahl1, T O Daniel, G Carpenter.
Abstract
A tenfold increase in phospholipase C activity specific for phosphatidylinositol 4,5-bisphosphate (PIP2) was immunopurified from extracts of A-431 epidermoid carcinoma cells stimulated with epidermal growth factor. This finding suggests a biochemical link between growth factor-stimulated tyrosine kinase activity and PIP2 hydrolysis.Entities:
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Year: 1988 PMID: 2457254 DOI: 10.1126/science.2457254
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728