| Literature DB >> 24571784 |
Qifan Wu1, Yan Zhang, Sunliang Cui.
Abstract
Copper-catalyzed cyclization of an oxime ester toward divergent heterocycle synthesis is reported. Oxime ester serves as an enamine precursor to cyclize with malononitrile and aldehydes for access to 2-aminonicotinonitriles in a one-pot reaction, while cyclizing with N-sulfonylimines leads to synthesis of pyrazolines.Entities:
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Year: 2014 PMID： 24571784 DOI： 10.1021/ol500094w
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005