| Literature DB >> 2457117 |
R D Shaw1, E R Mackow, M L Dyall-Smith, I Lazdins, I H Holmes, H B Greenberg.
Abstract
Neutralization escape mutants of simian rotaviruses (rhesus rotavirus and SA11) were tested in hemagglutination inhibition and neutralization assays against hyperimmune and infection sera to determine if mutation in an immunodominant epitope could enable neutralization escape. An SA11 mutant with a new glycosylation site at amino acid 211 of VP7 was shown to escape neutralization by hyperimmune but not infection sera.Entities:
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Year: 1988 PMID: 2457117 PMCID: PMC253479
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103